Astaxanthin the strong antioxidant, the red naturally miracle

Intro to Astaxanthin

Fish oil, DHA & EPA & OMEGA 3-6-9 Antioxidants and benefits

Raw fish

Astaxanthin is a reddish pigment that belongs to a group of chemicals called carotenoids. Astaxanthin is found in microalgae, yeast, salmon, trout, krill, shrimp, crayfish, crustaceans, and the feathers of some birds. It provides the red color of salmon meat and the red color of cooked shellfish. 

Astaxanthin the strong antioxidant, the red naturally miracle


Astaxanthin is Known for


Astaxanthin is known for treating Alzheimer’s disease, Parkinson’s disease, “brain attack” (stroke), high cholesterol, and an eye condition called age-related macular degeneration (AMD). It is also used for preventing cancer like many other antioxidants. Astaxanthin is sometimes applied directly to the skin for protection against sunburn and cure sunburn. source webmd
The primary use for humans is as a dietary supplement. Research suggests that, due to astaxanthin’s antioxidant activity that almost all fish oils and sea food related supplements has, it may be beneficial in cardiovascular, immune, inflammatory and neurodegenerative diseases. It is good for cardiovascular issues basically because these good type of fat helps body get rid of the bad kind of fat that in many cases sticks to the veins and blocks them and slows the blood flow and some other problems in body ability to burn the fat in body.
Some research supports the assumption that it may protect body tissues from oxidative and ultraviolet damage through its suppression of NF-κB activation. Thats why it may help you with sunburn that was mentioned earlier. 

What are Antioxidants & free-radicals? Antioxidants effects on aging, weight loss, Immune system


Get Astaxanthin for

 
1. Astaxanthin Helps with Pain and Inflammation 
2. Astaxanthin can Help Fight Fatigue
3. Astaxanthin Supports Eye Health
4. Astaxanthin Cleans Up the Cells 
5. Astaxanthin works as Skin and Sunscreen Protection
 
 

source webmd & wikipedia & hoffingtonpost


Astaxanthin the strong antioxidant, the red naturally miracle

Get Astaxanthin naturally



You can get Astaxanthin naturally by eating more seafoods like salmon, trout, lobster, shrimp, and other seafood.
Astaxanthin concentrations in natural sources as found in nature are approximately:

Source Astaxanthin concentration (ppm)
Salmonids ~ 5
Plankton ~ 60
Krill ~ 120
Arctic shrimp (P borealis) ~ 1,200
Phaffia yeast ~ 10,000
Haematococcus pluvialis ~ 40,000

source wikipedia


Side effects Astaxanthin


Astaxanthin is SAFE when consumed in amounts found in food like fish and shrimp in a regular meal. Astaxanthin is SAFE when taken by mouth as a supplement. 



Astaxanthin the strong antioxidant, the red naturally miracle

Dosing Astaxanthin


“Astaxanthin has been used safely by itself in doses of 4 to 40 mg daily for up to 12 weeks. It has been used safely in combination with other carotenoids, vitamins and minerals at 4 mg daily for up to 12 months.” source webmd

Special Precautions & Warnings:

“Pregnancy and breast-feeding: Not enough is known about the use of astaxanthin during pregnancy and breast-feeding. Stay on the safe side and avoid use.” source webmd


Web site sources:
Articles and papers use-ful on Astaxanthin and it benefits:
Articles and papers useful on Astaxanthin and it benefits:
 
1. Lee SJ, Bai SK, Lee KS, Namkoong S, Na HJ, Ha KS, Han JA, Yim SV, Chang K, Kwon YG, Lee SK, Kim YM. Astaxanthin inhibits nitric oxide production and inflammatory gene expression by suppressing I(kappa)B kinase-dependent NF-kappaB activation. Mol Cells. 2003 Aug 31;16(1):97-105. PubMed PMID: 14503852.
 
2. Kearney PM, Baigent C, Godwin J, Halls H, Emberson JR, Patrono C. Do selective cyclo-oxygenase-2 inhibitors and traditional non-steroidal anti-inflammatory drugs increase the risk of atherothrombosis? Meta-analysis of randomised trials. BMJ. 2006 Jun 3;332(7553):1302-8. PubMed PMID: 16740558; PubMed Central PMCID: PMC1473048.
 
3. Belknap SM. NSAIDs were associated with increased risk for mortality, regardless of time since first MI. Ann Intern Med. 2013 Jan 15;158(2):JC10. doi: 
10.7326/0003-4819-158-2-201301150-02010. PubMed PMID: 23318332.
 
4. Iwasaki Tsuneto, Tahara Akihiko. Effects of Astaxanthin on Eyestrain Induced by Accommodative Dysfunction. Journal of the Eye VOL.23;NO.6;829-834(2006)
 
5. Nagaki Y., Hayasaka S., Yamada T., Hayasaka Y., Sanada M., Uonomi T. Effects of Astaxanthin on accommodation, critical flicker fusion, and pattern visual evoked potential in visual display terminal workers. Journal of Traditional Medicines 2002: 19 (5), 170 – 173.
 
6. Nagaki Yasunori et al. The Effect of Astaxanthin on Retinal Capillary Blood Flow in Normal Volunteers. Journal of Clinical Therapeutics & Medicines Vol.21;No.5;537-542(2005)
 
7. Sun Z, Liu J, Zeng X, Huangfu J, Jiang Y, Wang M, Chen F. Protective actions of microalgae against endogenous and exogenous advanced glycation endproducts (AGEs) in human retinal pigment epithelial cells. Food Funct. 2011 May;2(5):251-8. doi: 10.1039/c1fo10021a. Epub 2011 Apr 21. PubMed PMID: 21779563.
 
8. Ishida S. Lifestyle-related diseases and anti-aging ophthalmology: suppression of retinal and choroidal pathologies by inhibiting renin-angiotensin system and inflammation. Article in Japanese: Nihon Ganka Gakkai Zasshi. 2009 Mar;113(3):403-22; discussion 423. Review. Japanese. PubMed PMID: 19348185.
 
9. Liao JH, Chen CS, Maher TJ, Liu CY, Lin MH, Wu TH, Wu SH. Astaxanthin interacts with selenite and attenuates selenite-induced cataractogenesis. Chem Res Toxicol. 2009 Mar 16;22(3):518-25. doi: 10.1021/tx800378z. PubMed PMID: 19193053.
 
10. Nishida Y. et. al, Quenching Activities of Common Hydrophilic and Lipophilic Antioxidants against Singlet Oxygen Using Chemiluminescence Detection System.
Carotenoid Science 11:16-20 (2007)
 
11. Iwamoto T, et al. Inhibition of low-density lipoprotein oxidation by astaxanthin. J Atherosc Thromb 2000;7:216-22.
 
12. Camera E, Mastrofrancesco A, Fabbri C, Daubrawa F, Picardo M, Sies H, Stahl W. Astaxanthin, canthaxanthin and beta-carotene differently affect UVA-induced oxidative damage and expression of oxidative stress- responsive enzymes. Exp Dermatol. 2009 Mar;18(3):222-31. Epub 2008 Sep
 
13. Yamashita, E. Beauty From Within: A Synergistic Combination Of Astaxanthin And Tocotrienol For Beauty Supplements (2002) Cosmetic Benefit of Dietary Supplements Containing Astaxanthin and Tocotrienol on Human Skin. Food Style 21 6(6):112-17.
 
14. A novel micronutrient supplement in skin aging: a randomized placebo-controlled double-blind study. Journal of Cosmetic Dermatology Volume 4 Page 277 – December 2005
 
15. Suganuma K, Nakajima H, Ohtsuki M, Imokawa G. Astaxanthin attenuates the UVA-induced up-regulation of matrix- metalloproteinase-1 and skin fibroblast elastase in human dermal fibroblasts. J Dermatol Sci. 2010 May;58(2):136-42. Epub 2010 Feb 18.
 
16. Arakane Kumi. Effect of Antioxidant to Inhibit UV-Induced Wrinkles. Journal of Japanese Cosmetic Science Society Vol. 27;No.4; 298-303(2003).
 
17. Aoi, et al, 2003. Astaxanthin limits exercise-induced skeletal and cardiac muscle damage in mice. Antioxid Redox Signal. 2003 Feb;5(1):139-44.
 
18. Curt L. Malmsten and Åke Lignell. Dietary Supplementation with Astaxanthin-Rich Algal Meal Improves Strength Endurance. A Double Blind Placebo Controlled Study on Male Students. Carotenoid Science, Vol.13, 2008 ISSN 1880-5671.
 
19. Aoi W, Naito Y, Takanami Y, Ishii T, Kawai Y, Akagiri S, Kato Y, Osawa T, Yoshikawa T. Astaxanthin improves muscle lipid metabolism in exercise via inhibitory effect of oxidative CPT I modification. Biochem Biophys Res Commun. 2008 Feb 22;366(4):892-7. Epub 2007 Dec 17.
 
20. Ikeuchi M, Koyama T, Takahashi J, Yazawa K. Effects of astaxanthin supplementation on exercise-induced fatigue in mice. Biol Pharm Bull. 2006 Oct;29(10):2106-10.
 
21. Gene A. Spiller, PhD, Antonella Dewell, MS, RD, Sally Chaves, RN, Zaga Rakidzich. Effect of daily use natural astaxanthin on C-reactive protein. Health Research & Studies Center, Los Altos, CA. Study Report, January, 2006.
 
22. Pearson, Thomas; Mensah, George, et al. Markers of inflammation and cardiovascular disease: application to clinical and public health practice: A statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association.2003 Jan 28; 107(3) :499-511.
 
23. Beutner, S., Bloedorn, B., Frixel, S., Hernández Blanco, I., Hoffmann, T., Martin, H.-D., Mayer, B., Noack, P., Ruck, C., Schmidt, M., Schülke, I., Sell, S., Ernst, H., Haremza, S., Seybold, G., Sies, H., Stahl, W. and Walsh, R. (2001), Quantitative assessment of antioxidant properties of natural colorants and phytochemicals: carotenoids, flavonoids, phenols and indigoids. The role of β-carotene in antioxidant functions. J. Sci. Food Agric., 81: 559-568. doi: 10.1002/jsfa.849.
 
24. Spallholz JE. Free radical generation by selenium compounds and their prooxidant toxicity. Biomed Environ Sci. 1997 Sep;10(2-3):260-70. Review. PubMed PMID: 9315319.
 
25. Koren R, Hadari-Naor I, Zuck E, Rotem C, Liberman UA, Ravid A. Vitamin D is a prooxidant in breast cancer cells. Cancer Res. 2001 Feb 15;61(4):1439-44. PubMed PMID: 11245448.
 
26. Pearson P, Lewis SA, Britton J, Young IS, Fogarty A. The pro-oxidant activity of high-dose vitamin E supplements in vivo. BioDrugs. 2006;20(5):271-3. PubMed PMID: 17025373.

27. Aoi, W., et al. (2004, July 5). Astaxanthin Limits Exercise-Induced Skeletal and Cardiac Muscle Damage in Mice. Antioxidants & Redox Signaling, 5(1), 139-144. Retrieved from http://online.liebertpub.com/doi/abs/10.1089/152308603321223630
28. Astaxanthin. (2014, September). Retrieved from http://www.med.nyu.edu/content?ChunkIID=160132
Bloomer, R. J., et al. (2005, August). Astaxanthin supplementation does not attenuate muscle injury following eccentric exercise in resistance-trained men. International Journal of Sport Nutrition and Exercise Metabolism, 15(4), 401-412. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/16286671
29. Comhaire, F. H., et al. (2005, September). Combined conventional/antioxidant “Astaxanthin” treatment for male infertility: a double blind, randomized trial. Asian Journal of Andrology, 7(3), 257-262. Retrieved fromhttp://www.ncbi.nlm.nih.gov/pubmed/16110353
30. Hussein, G., et al. (2006, April). Antihypertensive potential and mechanism of action of astaxanthin: III. Antioxidant and histopathological effects in spontaneously hypertensive rats. Biology and Pharmaceutical Bulletin, 29(4), 684-688. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/16595899
31. Ikeuchi, M., et al. (2006, October). Effects of astaxanthin supplementation on exercise-induced fatigue in mice. Biological and Pharmaceutical Bulletin, 29(10), 2106-2110. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/17015959
32. Kidd, P. (2011, December). Astaxanthin, cell membrane nutrient with diverse clinical benefits and anti-aging potential. Alternative Medicine Review, 16(4), 355-364. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/22214255 

33. Kimble, L., et al. (2013, March 30). Astaxanthin mediates inflammation biomarkers associated with arthritis in human chondrosarcoma cells induced with interleukin-1ß. American Journal of Advances Food Science and Technology, 2. 37-51. Retrieved from http://www.uscip.org/paper/ajafst/AJAFST%20-%20Astaxanthin%20Mediates%20Inflammation%20Biomarkers%20Associated%20with%20Arthritis%20in%20Human%20Chondrosarcoma%20Cells%20Induced%20with%20Interleukin-1B.pdf
34. MacDermid, J., et al. (2012, March). A blinded placebo-controlled randomized trial on the use of astaxanthin as an adjunct to splinting in the treatment of carpal tunnel syndrome. Hand, 7(1), 1-9. Retrieved fromhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280376/
35. Naguib, Y. (2000, April). Antioxidant activities of astaxanthin and related carotenoids. Journal of Agricultural and Food Chemistry, 48(4), 1150-1154. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/10775364
36. Teo, I., et al. (2005, November). Antiproliferation and induction of cell death of Phaffia rhodozyma (Xanthophyllomyces dendrorhous) extract fermented by brewer malt waste on breast cancer cells. International Journal of Molecular Medicine, 16(5), 931-936. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/16211266
37. Tominaga, K., et al. (2012, March). Cosmetic benefits of astaxanthin on human subjects. Acta Biochimica Polonica 59, 43–47. Retrieved from http://www.actabp.pl/pdf/1_2012/43.pdf