What Exactly Is the Keto Diet? And How It Helps Your Body Stay Healthy?

Ketogenic Diets Have “Profound Effect on Brain Function,” Studies Find

Ketogenic-Diet-Pryamid

Ketogenic Diet foods

Brain can’t burn fat for its outsized energy needs. It requires sugar. Or ketone bodies if you decide to starve your body of glucose. Eat lots of fat, consume fewer carbs, and voila. While I’m not overweight I dropped ten pounds in weeks when experimenting with ketosis. Ever since I’ve maintained this weight, not by fasting—a popular ketogenic method is to fast for between 12 and 18 hours every day—but by keeping carb consumption down and fat intake high, also supported by recent research on 135,000 adults.

Ketogenic-Diet-Pryamid

Ketogenic Diet Pryamid

 

Studies on Keto

Ketogenic Diet Reduces Midlife Mortality and Improves Memory in Aging Mice

The study shows “that a non-obesogenic ketogenic diet improves survival, memory, and healthspan in aging mice.”

In the first study, mice were fed three diets: zero carbohydrates, a nutrient-balanced diet (the control group), and a high fat diet with just 15 percent carbohydrate intake, a percentage arrived at when researchers slowly added carbs to a carb-restricted diet to find the baseline in which mice remain in ketosis. After 15 percent their bodies suppressed ketosis, and would be little different than the control group.

The mice were put on a cyclic ketogenic, high-fat, or control diet in mid-life. The cycle was one week, so they would eat this way for a week, then every mouse would spend a week on their respective diets. (Ketogenic- and high-fat only mice did not fare as well.) Interestingly, the high-fat group ended up heaviest, though the ketogenic and high-fat groups both had a higher caloric intake than the control group. In terms of longevity, the ketonic group proved most successful, at least through midlife. After thirty months of age, their mortality rate was the same as the control and high-fat groups.

As for memory, the researchers write:

In healthspan testing, we found a striking effect of Cyclic KD [ketogenic diet] on memory as well as more modest effects on a broader range of measures. We saw consistent memory improvement in two distinct tasks over 6 months.

The ketogenic group showed normal cognition wear with aging, but performed better in a visuospatial learning and memory test than the other groups, in which the mice learned to avoid (or not) an electric shock. The KD mice also showed improvement in late middle age (28-30 months) in novel object recognition.

Foods to avoid in KETO

keto foods to avoid

keto foods to avoid

 

(As one researcher, molecular biologist Eric Verdi )The researchers state that:

“We’re very excited to see such a profound effect on brain function. Our results don’t imply this is going to work in humans. For that, we’ll need extensive clinical trials.”

 

 

 

How antioxidants like HCA & CGA & POLYPHENOLS help burn more fat

Some antioxidants (foods) helps you lose weight | How antioxidants like HCA & CGA & POLYPHENOLS help burn more fat

 

 

Which antioxidant can help you lose weight:

  1. HCA hydroxycitric acid (found in garcinia cambogia)
  2. CGA Chlorogenic Acid (found in green coffee extract) (is of course a form of polyphenol antioxidant)
  3. POLYPHENOLS (PHENOLIC ACID) (found in green tea, berries, and…)

 

HCA hydroxycitric acid CGA Chlorogenic Acid POLYPHENOLS (PHENOLIC ACID)

HCA hydroxycitric acid,  CGA Chlorogenic Acid,  POLYPHENOLS (PHENOLIC ACID)

 

1. HCA hydroxycitric acid (antioxidant) in garcinia cambogia can help you lose weight:

  • hydroxycitric acid Helps your storage of body fats come into action and be used in long term
  • Blocks storage of the extra calories you do not use as fat in your body
  • hydroxycitric acid Increase lipid oxidation there by help to breakdown and remove fatty acids from your body
  • It may also help to decrease appetite to some degree
  • hydroxycitric acid may also help to lower triglyceride and low-density lipoprotein, or “LDL,” levels
  • Hydroxycitric acid is used to improve exercise performance too by limiting the use of stored energy in the muscles, which seems to prevent fatigue.

 

2. Chlorogenic Acid (found in green coffee extract) can help you lose weight:

  • Reduce the absorption of carbohydrates from the digestive tract
  • lowers blood sugar and insulin spikes
  • reduce fat absorbed from the diet
  • reduce fat stored in the liver
  • improve the function of the fat burning hormone adiponectin

 

3. POLYPHENOLS (PHENOLIC ACID) (found in green tea, berries, and…)

  • POLYPHENOLS (PHENOLIC ACID) in green tea are believed to block fat from being absorbed
  • POLYPHENOLS (PHENOLIC ACID) compounds in Green tea extract decreases starch digestion and absorption, Green tea extract blocks an enzyme that breaks down carbs
  • Green Tea May Prevent Weight Gain by Inhibiting Fat Absorption and Promoting Fat Use.

 

 

Main factor in losing weight

Losing weight is not a “one factor problem” that gets solved with one solution. many factors are involved in a healthy weight loss. Exercise is very important as diet is. What you eat generally determines how your body works. If you eat a hot spicy food you will expect your appropriate body reaction. As explained in earlier post about how sugar can contribute to agingour body fuel system is very complex and complicated. You can not just eat what ever randomly and assume it has no effect on you and how you perceive and how your body acts. We basically get energy from 4 different category of foods: Fat, carbohydrates, sugar, protein. our body has different hormones and enzymes to make every one of these into energy and use them. Sugar is very tasty right? thats because it burns fast and is vital so has almost the first priority for our body to be used. The extras always go to storage for later use. So when you have sugar you dont burn fat and also the extra sugar and all go to be stored as fat in your storage areas. this metabolism is critically dependent on what you eat. What you eat determines what your body does and feel. for more detailes on this read sugar and aging.

But how some antioxidants can actually help you lose weight and play a role in the complicated system of our body metabolism. hydroxycitric acid or HCA is know to be able to in some way help you lose weight. but let talk about how hydroxycitric acid (HCA) actually does it as an antioxidant agent found in some foods like garcinia cambogia. Hydroxycitric acid is derived from the dried rind of the fruit that grows on the Garcinia cambogia tree, which it is native to India, Malaysia and Africa. Hydroxycitric acid contains numerous phytochemicals including xanthones, flavanoids and benzophenones. Phytochemicals are antioxidant compounds found in plants that help to prevent free radical induced damage.

 

 

Hydroxycitric acid has become popular as a weight loss aid. It has been found to increase lipid oxidation and thereby help to breakdown and remove fatty acids from your body. It may also help to decrease appetite, and a six-week, placebo controlled study cited in the June 2002 edition of “International Journal of Obesity-Related Metabolic Disorders” examined the effectiveness of hydroxycitric acid as an appetite suppressant. The study found that hydroxycitric acid supplementation decreased the daily caloric intake in overweight individuals by 15 to 30 percent. The participants experienced weight loss, whilst also reporting feelings of satiety. HCA Hydroxycitric acid has also anti-inflammatory properties and is used to help treat inflammatory bowel disorders. More research needs to be done to confirm the efficacy of hydroxycitric acid for these uses however.

A lot of research has been done on the effects of a high antioxidant diet, they have been inconclusive on their direct effect on weight loss. As mentioned before many thing play important roles in healthy weight loss and antioxidants like HCA can help you a lot in how your metabolism works. 

Antioxidants are known to turn toxins in the body into harmless elements. Toxins are readily stored in fat cells. Therefore the more toxins we have in our body, the more our bodies will willingly ‘hold on’ to these fat cells in order to prevent toxins from freely roaming in our bodies. This is usually noticed by people who exercise and reach a plateau in their weight loss curve and in those who have slow metabolism rates. In order to reverse this, a diet rich in antioxidants has been shown to have numerous benefits.

While green tea can increase energy and enhance physical performance, there are no clear studies that indicate that the weight loss supplement boosts metabolism. The HCA in Garcinia Cambogia, however, jumpstarts the metabolism so that the body will burn fat at a faster rate. This makes for more permanent weight loss and can help dieters to avoid the yo-yo effect that sometimes comes with taking a weight loss product. Garcinia Cambogia is also high in fiber, which is a quality green tea doesn’t possess. Fiber helps to balance the blood sugar and moves food along the digestive tract speedily.

 

 

Although antioxidants have not been directly linked to fat burning, it is a wonder that people who consume foods rich in antioxidants tend to lose weight. In a study done with overweight participants, those who included green tea in their diet lost more weight compared to the control group. The same has been noted with the intake of water infused with lemon rinds. Lemons and green tea are both very good sources of antioxidants.

For fat loss to occur, the body has to convert stored fat into glucose to provide it with energy. Although no conclusive evidence has been found, research suggests that a diet rich in antioxidants can convert your body from a sugar burning to a fat burning machine. This means that instead of using up the sugars you ingest to produce energy, the body will use stored fats. Antioxidants found in green tea have been found to possibly cut through fat stored in the body.

More research is yet to be done on the benefits of increasing your intake of antioxidant. However, what is clear is that it is better to take them in their natural form rather than in supplements because foods containing antioxidants have other benefits too.

 

 

There have been several human studies on Green Coffee Bean Extract. These studies are so-called randomized controlled trials, which are the gold standard of scientific experiments in humans. One of them included 30 overweight individuals and went on for 12 weeks. There were two groups… one consumed regular Instant coffee, while the other consumed Instant coffee enriched with 200 mg of Green Coffee Bean Extract. Neither group was instructed to change their diet or exercise habits. This graph shows the weight changes in the two groups, from 0-12 weeks:

As you can see, the group taking the instant coffee with green coffee bean extract lost 11.9 pounds (5.4 kg), while the group taking plain instant coffee lost only 3.7 pounds (1.7 kg).

Body fat percentage also went down by 3.6% in the green coffee extract group, compared to 0.7% in the other group.

 

White kidney beans extracts and storage of energy as body fat

There are different ideas about White kidney beans extracts so we did not include them in the antioxidants that helps you lose weight.

White beans and other foods with a low glycemic score also offer extraordinary weight loss benefits. When the carbohydrates in our food cause our blood sugar levels to rise, a polypeptide hormone called insulin is produced by the pancreas (a large gland organ located behind the stomach). The purpose of insulin is to bring the elevated blood sugar levels back down by stimulating the uptake of glucose (sugar) by the body’s cells which can then use the glucose for energy. However, if the blood sugar levels are very high (e.g. after a high GI meal), insulin will cause some of the blood sugar to be stored as fat (for later use as energy). Low GI foods like beans have the opposite effect. Great news for those who are following a fat loss diet plan! In addition to their gentle effect on blood sugar levels, white beans may provide weight loss benefits due their ability to produce alpha-amylase inhibitors. Alpha-amylase inhibitors are known to slow the absorption of carbohydrates (and thus the storage of energy as body fat) by inhibiting enzymes responsible for cutting starches into simpler sugars.

Antioxidants in white kidney beans promote good health and wrinkle-free skin: White beans deliver a hefty supply of antioxidants, substances that fight off disease and help maintain optimum health. Antioxidants are believed to protect the cells in your body from free radicals, unstable molecules that damage cells. Ultimately, the damage caused by free radicals can result in many chronic conditions and degenerative diseases including certain types of cancer, atherosclerosis, thrombosis, arthritis, heart disease, immune system problems, Alzheimer’s disease, and dementia. source

What Are Starch Blockers like White kidney beans extracts?

Starches are complex carbohydrates that cannot be absorbed unless they are first broken down by the digestive enzyme amylase. Amylase inhibitors, also called starch blockers, prevent starches from being absorbed by the body. When amylase is blocked, those carbs pass through the body undigested, so you don’t absorb the calories.

Prescription drugs have to prove to the FDA that they are safe and effective. Supplements don’t. You also can’t be sure of what’s in a supplement.

Some supplements may have unlisted ingredients, maybe stimulants, that could be dangerous for people with diabetes, says Kathleen Dungan, MD, an endocrinologist at Ohio State University.

Prescription versions won’t have those extra ingredients, so they tend to be safer.

The FDA has sent warning letters to makers of no-prescription starch blockers in the past, saying their marketing claims are misleading.

If you’re considering using any product marketed for weight loss, talk to your doctor or a dietitian first. Ask yourself if it sounds too good to be true, and be skeptical.

Source

 

 

 

Sources and online websites about losing weight and antioxidants:

 

http://www.livestrong.com/article/429560-hydroxycitric-acid-information/

https://www.ncbi.nlm.nih.gov/pubmed/21401105

https://www.ncbi.nlm.nih.gov/pubmed/20933071

https://www.drugs.com/npp/garcinia-hydroxycitric-acid.html

 

 

 

Papers and references about losing weight and antioxidants:

 

1. Abraham Z, Malik SK, Rao GE, Narayanan SL, Biju S. Collection and characterization of Malabar tamarind [ Garcinia cambogia (Gaertn.) Desr.]. Genet Resour Crop Evol . 2006;53(2):401-406.
2. Soni MG, Burdock GA, Preuss HG, Stohs SJ, Ohia SE, Bagchi D. Safety assessment of (-)-hydroxycitric acid and Super CitriMax, a novel calcium/potassium salt. Food Chem Toxicol . 2004;42(9):1513-1529.
3. Ohia SE, Opere CA, LeDay AM, Bagchi M, Bagchi D, Stohs SJ. Safety and mechanism of appetite suppression by a novel hydroxycitric acid extract (HCA-SX). Mol Cell Biochem . 2002;238(1-2):89-103.
4. Saito M, Ueno M, Ogino S, Kubo K, Nagata J, Takeuchi M. High dose of Garcinia cambogia is effective in suppressing fat accumulation in developing male Zucker obese rats, but highly toxic to the testis. Food Chem Toxicol . 2005;43(3):411-419.
5. Jena BS, Jayaprakasha GK, Singh RP, Sakariah KK. Chemistry and biochemistry of (-)-hydroxycitric acid from Garcinia . J Agric Food Chem . 2002;50(1):10-22.
6. Masullo M, Bassarello C, Suzuki H, Pizza C, Piacente S. Polyisoprenylated benzophenones and an unusual polyisoprenylated tetracyclic xanthone from the fruits of Garcinia cambogia . J Agric Food Chem . 2008;56(13):5205-5210.
7. Koshy AS, Anila L, Vijayalakshmi NR. Flavonoids from Garcinia cambogia lower lipid levels in hypercholesterolemic rats. Food Chem . 2001;72(3):289-294.
8. Downs BW, Bagchi M, Subbaraju GV, Shara MA, Preuss HG, Bagchi D. Bioefficacy of a novel calcium-potassium salt of (-)-hydroxycitric acid. Mutat Res . 2005;579(1-2):149-162.
9. Hida H, Yamada T, Yamada Y. Production of hydroxycitric acid by microorganisms. Biosci Biotechnol Biochem . 2005;69(8):1555-1561.
10. Yamada T, Hida H, Yamada Y. Chemistry, physiological properties, and microbial production of hydroxycitric acid. Appl Microbiol Biotechnol . 2007;75(5):977-982.
11. Berkhout TA, Havekes LM, Pearce NJ, Groot PH. The effect of (-)-hydroxycitrate on the activity of the low-density-lipoprotein receptor and 3-hydroxy-3-methylglutaryl-CoA reductase levels in the human hepatoma cell line Hep G2. Biochem J . 1990;272(1):181-186.
12. Mahendran P, Devi CS. Effect of Garcinia cambogia extract on lipids and lipoprotein composition in dexamethasone administered rats. Indian J Physiol Pharmacol . 2001;45(3):345-350.
13. Girola M, De Bernardi M, Contos S, et al. Dose effect in lipid-lowering activity of a new dietary integrator (chitosan), Garcinia combogia extract and chrome. Acta Toxicol Ther . 1996;17(1):25-40.
14. Mattes RD, Bormann L. Effects of (-)-hydroxycitric acid on appetitive variables. Physiol Behav . 2000;71(1-2):87-94.
15. Kim YJ, Kim KY, Kim MS, Lee JH, Lee KP, Park T. A mixture of the aqueous extract of Garcinia cambogia , soy peptide and L: -carnitine reduces the accumulation of visceral fat mass in rats rendered obese by a high fat diet. Genes Nutr . 2008;2(4):353-358.
16. Kim KY, Lee HN, Kim YJ, Park T. Garcinia cambogia extract ameliorates visceral adiposity in C57BL/6J mice fed on a high-fat diet. Biosci Biotechnol Biochem . 2008;72(7):1772-1780.
17. Leray V, Dumon H, Martin L, et al. No effect of conjugated linoleic acid or Garcinia cambogia on fat-free mass, and energy expenditure in normal cats. J Nutr . 2006;136(suppl 7):1982S-1984S.
18. Thom E. A randomized, double-blind, placebo-controlled trial of a new weight-reducing agent of natural origin. J Int Med Res . 2000;28(5):229-233.
19. Lau FC, Bagchi M, Sen C, Roy S, Bagchi D. Nutrigenomic analysis of diet-gene interactions on functional supplements for weight management. Curr Genomics . 2008;9(4):239-251.
20. Talpur N, Echard BW, Yasmin T, Bagchi D, Preuss HG. Effects of niacin-bound chromium, Maitake mushroom fraction SX and (-)-hydroxycitric acid on the metabolic syndrome in aged diabetic Zucker fatty rats. Mol Cell Biochem . 2003;252(1-2):369-377.
21. Bagchi D, Deshmukh NS, Soni MG, Bagchi M. Safety of a novel calcium/potassium salt of (-)-hydroxycitric acid: I. Two generation reproduction toxicity study. Toxicol Lett . 2007;172(suppl 1):S190.
22. Asghar M, Monjok E, Kouamou G, Ohia SE, Bagchi D, Lokhandwala MF. Super CitriMax (HCA-SX) attenuates increases in oxidative stress, inflammation, insulin resistance, and body weight in developing obese Zucker rats. Mol Cell Biochem . 2007;304(1-2):93-99.
23. Preuss HG, Rao CV, Garis R, et al. An overview of the safety and efficacy of a novel, natural(-)-hydroxycitric acid extract (HCA-SX) for weight management. J Med . 2004;35(1-6):33-48.
24. Hayamizu K, Ishii Y, Kaneko I, et al. Effects of Garcinia cambogia (hydroxycitric acid) on visceral fat accumulation: A double-blind, randomized, placebo-controlled trial. CurrTher Res Clin Exp . 2003;64(8):551-567.
25. Heymsfield SB, Allison DB, Vasselli JR, Pietrobelli A, Greenfield D, Nunez C. Garcinia cambogia (hydroxycitric acid) as a potential antiobesity agent: a randomized controlled trial. JAMA . 1998;280(18):1596-1600.
26. Yonei Y, Takahashi Y, Hibino S, Watanabe M, Yoshioka T. Effects on the human body of a dietary supplement containing L-carnitine and Garcinia cambogia extract: a study using double-blind tests. J Clin Biochem Nutr . 2008;42(2):89-103.
27. Mazzio EA, Soliman KF. In vitro screening for the tumoricidal properties of international medicinal herbs. Phytother Res . 2009;23(3):385-398.
28. Hayamizu K, Hirakawa H, Oikawa D, et al. Effect of Garcinia cambogia extract on serum leptin and insulin in mice. Fitoterapia . 2003;74(3):267-273.
29. Wielinga PY, Wachters-Hagedoorn RE, Bouter B, et al. Hydroxycitric acid delays intestinal glucose absorption in rats. Am J Physiol Gastrointest Liver Physiol . 2005;288(6):G1144-G1149.
30. Ishihara K, Oyaizu S, Onuki K, Lim K, Fushiki T. Chronic (-)-hydroxycitrate administration spares carbohydrate utilization and promotes lipid oxidation during exercise in mice. J Nutr . 2000;130(12):2990-2995.
31. Hoffman JR, Kang J, Ratamess NA, Jennings PF, Mangine G, Faigenbaum AD. Thermogenic effect from nutritionally enriched coffee consumption. J Int Soc Sports Nutr . 2006;3:35-41.
32. Taylor LW, Wilborn CD, Harvey T, Wismann J, Willoughby DS. Acute effects of ingesting Java Fittrade mark energy extreme functional coffee on resting energy expenditure and hemodynamic responses in male and female coffee drinkers. J Int Soc Sports Nutr . 2007;4:10.
33. Mahendran P, Sabitha KE, Devi CS. Prevention of HCl-ethanol induced gastric mucosal injury in rats by Garcinia cambogia extract and its possible mechanism of action. Indian J Exp Biol . 2002;40(1):58-62.
34. Mahendran P, Vanisree AJ, Shyamala Devi CS. The antiulcer activity of Garcinia cambogia extract against indomethacin-induced gastric ulcer in rats. Phytother Res . 2002;16(1):80-83.
35. dos Reis SB, de Oliveira CC, Acedo SC, et al. Attenuation of colitis injury in rats using Garcinia cambogia extract. Phytother Res . 2009;23(3):324-329.
36. Oluyemi KA, Omotuyi IO, Jimoh OR, Adesanya OA, Saalu CL, Josiah SJ. Erythropoietic and anti-obesity effects of Garcinia cambogia (bitter kola) in Wistar rats. Biotechnol Appl Biochem . 2007;46(pt 1):69-72.
37. Deshmukh NS, Bagchi M, Yasmin T, Bagchi D. Safety of a novel calcium/potassium salt of (-) hydroxycitric acid (HCA-SX): II. Developmental toxicity study in rats. Toxicol Mech Methods . 2008;18(5):443-451.
38. Kaur G, Kulkarni SK. Investigations on possible serotonergic involvement in effects of OB-200G (polyherbal preparation) on food intake in female mice. Eur J Nutr . 2001;40(3):127-133.
39. Actis GC, Bugianesi E, Ottobrelli A, Rizzetto M. Fatal liver failure following food supplements during chronic treatment with montelukast. Dig Liver Dis . 2007;39(10):953-955.
40. Mansi IA, Huang J. Rhabdomyolysis in response to weight-loss herbal medicine. [Published correction appears in: Am J Med Sci . 2004;328(2):129.] Am J Med Sci . 2004;327(6):356-357.
41. Ferris DJ. Interaction between warfarin and Garcinia cambogia (Fat Burner); a case report. ASHP Midyear Clinical Meeting . 38(DEC): p P-404(D). 2003.
42. Pittler MH, Schmidt K, Ernst E. Adverse events of herbal food supplements for body weight reduction: systematic review. Obes Rev . 2005;6(2):93-111.
43. Shim M, Saab S. Severe hepatotoxicity due to Hydroxycut: a case report. Dig Dis Sci . 2009;54(2):406-408.
44. Lobb A. Hepatoxicity associated with weight-loss supplements: a case for better post-marketing surveillance. World J Gastroenterol . 2009;15(14):1786-1787.
45. Anno T, Oono H, Tamura K. Improvement of testicular toxicity in F/344DuCrj male rats fed Ca-type Garcinia cambogia extract by zinc supplemented diets. Nippon Shokuhin Kagaku Gakkaishi . 2005;12(3):121-127.
46. Shara M, Ohia SE, Yasmin T, et al. Dose- and time-dependent effects of a novel (-)-hydroxycitric acid extract on body weight, hepatic and testicular lipid peroxidation, DNA fragmentation and histopathological data over a period of 90 days. Mol Cell Biochem . 2003;254(1-2):339-346.
47. Burdock G, Soni M, Bagchi M, Bagchi D. Garcinia cambogia toxicity is misleading. [Published correction appears in: Food Chem Toxicol . 2007;45(3):515.] Food Chem Toxicol . 2005;43(11):1683-1684; author reply 1685-1686.
48. Min B, McBride BF, Kardas MJ, et al. Electrocardiographic effects of an ephedra-free, multicomponent weight-loss supplement in healthy volunteers. Pharmacotherapy . 2005;25(5):654-659.
49. Hayamizu K, Tomi H, Kaneko I, Shen M, Soni MG, Yoshino G. Effects of Garcinia cambogia extract on serum sex hormones in overweight subjects. Fitoterapia . 2008;79(4):255-261.

 

Antioxidants Benefits & Effects of Polyphenols, Phenolic Acid

Polyphenols (Phenolic Acid) | Antioxidant Benefits & Effects on our body

Flavones Flavonols Flavanones Isoflavones Anthocyanidins Chalcones, Catechins,Stilbenes

Research in progress

 

About Polyphenol, Phenolic acids:

A phenolic acid is a sort of phytochemical known as a polyphenol. Phenolic acids are found in an assortment of plant-based nourishments such as the seeds and skins of products of the soil leaves of vegetables contain the most noteworthy concentration. Phenolic acids are promptly consumed through the dividers of your intestinal tract, and they might be valuable to your wellbeing since they fill in as cancer prevention agents that counteract cell harm because of free-radical oxidation responses. The Polyphenol phenolic acid supplements may likewise work as anti inflammatory in the human body. It strongly supports a role for polyphenols in the prevention of degenerative diseases, particularly cardiovascular diseases and cancers. The antioxidant properties of polyphenols have been widely studied, but it has become clear that the mechanisms of action of polyphenols go beyond the modulation of oxidative stress. Polyphenols are the most abundant antioxidants in the diet. Their total dietary intake could be as high as 1 g/d, which is much higher than that of all other classes of phytochemicals and known dietary antioxidants.

 

 

 

 

 

Ranking list of top foods list with Polyphenols (Phenolic Acid)

Polyphenols (Phenolic Acid) | Antioxidant Benefits & Effects on our body

Top foods list with Polyphenols (Phenolic Acid) | Antioxidant Benefits & Effects

Different Types of Polyphenols

Polyphenols are four main categories, with additional sub-groupings. based on the number of phenol rings they contain, and on the basis of structural elements in their construction.

As a general rule, foods contain complex mixtures of polyphenols, with higher levels found in the outer layers of the plants than the inner parts.

 

1- Flavonoids,  have Strong both antioxidant and anti-inflammatory properties, found in fruits, vegetables, legumes, red wine, and green tea
      Flavones
      Flavonols
      Flavanones
      Isoflavones
      Anthocyanidins
      Chalcones
      Catechins
2- Stilbenes, found in red wine and peanuts (resveratrol is the most well known)
3- Lignans, found in seeds like flax, legumes, cereals, grains, fruits, algae, and certain vegetables
4- Phenolic acids
Hydroxybenzoic acids, found in tea
Hydroxycinnamic acids found in cinnamon of course but also in coffee, blueberries, kiwis, plums, apples, and cherries

 

Polyphenols (Phenolic Acid) | Antioxidant Benefits & Effects on our body

 

Polyphenols are usually associated with/ improving:

  • Fighting cancer cells and inhibiting angiogenesis (the growth of blood vessels that feed a tumor)
  • Protecting your skin against ultraviolet radiation
  • Fighting free radicals
  • reducing the appearance of aging
  • Promoting brain health
  • protecting against dementia
  • Reducing inflammation
  • Supporting normal blood sugar levels
  • Protecting your cardiovascular system
  • Promoting normal blood pressure

 

Polyphenols work effective for :

 

 

 

Antioxidants effects & Benefits of Phenolic acids:

• Anti-Diabetic Effects of  Polyphenols

Numerous studies report the antidiabetic effects of polyphenols. Tea catechins have been investigated for their anti-diabetic potential.63,64 Polyphenols may affect glycemia through different mechanisms, including the inhibition of glucose absorption in the gut or of its uptake by peripheral tissues.Onion polyphenols, especially quercetin is known to possess strong anti diabetic activity. A recent study shows that quercetin has ability to protect the alterations in diabetic patients during oxidative stress. Quercetin significantly protected the lipid peroxidation and inhibition antioxidant system in diabetics. (source)

Cranberry Strong Antioxidant Effects

 

• Used as Anti bacterial:

Bacteria are collection of single cell microorganisms. Most microorganisms are innocuous in people because of the defensive impacts of the immune framework. Notwithstanding, a few microscopic organisms are perilous and can bring about irresistible maladies. Luckily, phenol acids are effective antibacterials and can help guard you from perilous microorganisms. Temporary reviews recommend that phenolic acid may likewise have antibacterial properties however additional confirmation is required before this can be affirmed. (source)

 Sage, just a mint or strong antioxidants and Anti-Inflammatory

• Anti-Aging Effect

Aging is the accumulation process of diverse detrimental changes in the cells and tissues with advancing age, resulting in an increase in the risks of disease and death. Among many theories purposed for the explaining the mechanism of aging, free radical/oxidative stress theory is one of the most accepted one. Antioxidant capacity of the plasma is related to dietary intake of antioxidants; it has been found that the intake of antioxidant rich diet is effective in reducing the deleterious effects of aging and behavior. Several researches suggest that the combination of antioxidant/anti-inflammatory polyphenolic compounds found in fruits and vegetables may show efficacy as anti-aging compounds. Subset of the flavonoids known as anthocyanins, are particularly abundant in brightly colored fruits such as berry fruits and concord grapes and grape seeds.  (source)

• Reduces inflammation:

Inflammation is the body’s method for managing disease, harm, aggravation or stress. It prompts warm, torment, redness or swelling around the influenced body part. Most inflammation is sure as it demonstrates that the body has recognized a risk and is endeavoring to manage the issue. In any case, some inflammation is superfluous and harms the body’s cells when there is no contamination, damage, bothering or worry to manage. Luckily, the phenolic acids can help monitor pointless inflammation. The strong antioxidants of phenolic acids are powerful against inflammation. (source)

Ranking list of top foods list with Polyphenols (Phenolic Acid)

• Antioxidant effects of Polyphenol, phenolic acid on cancer:

Antioxidants are substances that protect a human body’s cells from free radicals. Free radicals are destructive substances that are discharged into the body amid oxygen based responses. They have been connected with serious disease such as cancer, diabetes, a weak invulnerable system along with noticeable indications of maturing. Luckily, the greater parts of the phenolic acids aside from “capsaicin” are intense cancer prevention agents that can guard you from the antagonistic impacts related with free radicals. Several mechanisms of action have been identified for chemoprevention effect of polyphenols, these include estrogenic/antiestrogenic activity, antiproliferation, induction of cell cycle arrest or apoptosis, prevention of oxidation, induction of detoxification enzymes, regulation of the host immune system, anti-inflammatory activity and changes in cellular signaling

Ranking list of top foods list with Polyphenols (Phenolic Acid)

 

• Neuro-Protective Effects and Mental health boosters:

The phenolic acids have a considerable measure of potential with regards to boosting the emotional wellbeing. Early research proposes that phenolic acids may go about as an energizer and furthermore it prevents the Alzheimer’s disease. What’s more, they may likewise ensure against Alzheimer’s malady while vanillin may shield the cerebrum cells from harm, prevents Alzheimer’s infection and Parkinson’s ailment. In any case, additionally studies are required before the impacts of the phenolic acids on brain health are affirmed. Oxidative stress and damage to brain macromolecules is an important process in neurodegenerative diseases. Alzheimer’s disease is one of the most common occurring neurodisorder affecting up to 18 million people worldwide. Because polyphenols are highly antioxidative in nature, their consumption may provide protection in neurological diseases. It was observed that the people drinking three to four glasses of wine (vines that have Polyphenol contents) per day had 80% decreased incidence of dementia and Alzheimer’s disease compared to those who drank less or did not drink at all. (source)

 

Green Tea, Antioxidant effects and benefits

Polyphenol Supplements interactions

These mostly happen with supplements not the foods containing Polyphenol

  • Iron depletion in populations of people who have marginal iron stores
  • Interference with thyroid hormone metabolism
  • Interactions with pharmaceutical drugs, enhancing their biologic effects

 

 

 

 

 

 

 

 

 

References and sources for Polyphenols online:

http://www.nature.com/ejcn/journal/v64/n3s/fig_tab/ejcn2010221t1.html

http://articles.mercola.com/sites/articles/archive/2015/12/14/polyphenols-benefits.aspx

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835915/

https://en.wikipedia.org/wiki/Antioxidant_effect_of_polyphenols_and_natural_phenols

http://ajcn.nutrition.org/content/81/1/215S.full

 

 

Published papers and articles  and References for Polyphenols

1. Scalbert A, Manach C, Morand C, Remesy C. Dietary polyphenols and the prevention of diseases. Crit Rev Food Sci Nutr. 2005;45:287–306. [PubMed]
2. Spencer JP, Abd El Mohsen MM, Minihane AM, Mathers JC. Biomarkers of the intake of dietary polyphenols: strengths, limitations and application in nutrition research. Br J Nutr. 2008;99:12–22. [PubMed]
3. Beckman CH. Phenolic-storing cells: keys to programmed cell death and periderm formation in wilt disease resistance and in general defence responses in plants? Physiol. Mol. Plant Pathol. 2000;57:101–110.
4. Graf BA, Milbury PE, Blumberg JB. Flavonols, flavonones, flavanones and human health: Epidemological evidence. J Med Food. 2005;8:281–290. [PubMed]
5. Arts ICW, Hollman PCH. Polyphenols and disease risk in epidemiologic studies. Am J Clin Nutr. 2005;81:317–325. [PubMed]
6. Kondratyuk TP, Pezzuto JM. Natural Product Polyphenols of Relevance to Human Health. Pharm Biol. 2004;42:46–63.
7. Shahidi F, Naczk M. Food phenolics, sources, chemistry, effects, applications. Lancaster, PA: Technomic Publishing Co Inc; 1995.
8. de Groot H, Rauen U. Tissue injury by reactive oxygen species and the protective effects of flavonoids. Fundam Clin Pharmacol. 1998;12:249–255. [PubMed]
9. Adlercreutz H, Mazur W. Phyto-oestrogens and Western diseases. Ann Med. 1997;29:95–120. [PubMed]
10. Wink M. Compartmentation of secondary metabolites and xenobiotics in plant vacuoles. Adv Bot Res. 1997;25:141–169.
11. Simon BF, Perez-Ilzarbe J, Hernandez T, Gomez-Cordoves C, Estrella I. Importance of phenolic compounds for the characterization of fruit juices. J Agric Food Sci. 1992;40:1531–1535.
12. Manach C, Scalbert A, Morand C, Rémésy C, Jimenez L. Polyphenols: food sources and bioavailability. Am J Clin Nutr. 2004;79:727–747. [PubMed]
13. Parr AJ, Bolwell GP. Phenols in the plant and in man. The potential for possible nutritional enhancement of the diet by modifying the phenol content or profile. J Agric Food Chem. 2000;80:985–1012.
14. Sosulski FW, Krygier K, Hogge L. Importance of phenolic compounds for the characterization of fruit juices. J Agric Food Chem. 1982;30:337–340.
15. Price KR, Bacon JR, Rhodes MJC. Effect of storage and domestic processing on the content and composition of flavonol glucosides in onion (Allium cepa) J Agric Food Chem. 1997;45:938–942.
16. Crozier A, Lean MEJ, McDonald MS, Black C. Quantitative analysis of the flavonoid content of commercial tomatoes, onions, lettuce, and celery. J Agric Food Chem. 1997;45:590–595.
17. D’Archivio M, Filesi C, Benedetto RD, Gargiulo R, Giovannini C, Masella R. Polyphenols, dietary sources and bioavailability. Ann Ist Super Sanità 2007;43:348–361. [PubMed]
18. Day AJ, Williamson G. Biomarkers for exposure to dietary flavonoids: a review of the current evidence for identification of quercetin glycosides in plasma. Br J Nutr. 2001;86:S105–S110. [PubMed]
19. Setchell KD, Faughnan MS, Avades T, Zimmer-Nechemias L, Brown NM, et al. Comparing the pharmacokinetics of daidzein and genistein with the use of 13C-labeled tracers in premenopausal women. Am J Clin Nutr. 2003;77:411–419. [PubMed]
20. Duthie GG, Pedersen MW, Gardner PT, Morrice PC, Jenkinson AM, McPhail DB, Steele GM. The effect of whisky and wine consumption on total phenol content and antioxidant capacity of plasma from healthy volunteers. Eur J Clin Nutr. 1998;52:733–736. [PubMed]
21. Young JF, Nielsen SE, Haraldsdóttir J, Daneshvar B, Lauridsen ST, Knuthsen P, Crozier A, Sandström B, Dragsted LO. Effect of fruit juice intake on urinary quercetin excretion and biomarkers of antioxidative status. Am J Clin Nutr. 1999;69:87–94. [PubMed]
22. Gee JM, DuPont MS, Rhodes MJ, Johnson IT. Quercetin glucosides interact with the intestinal glucose transport pathway. Free Radic Biol Med. 1998;25:19–25. [PubMed]
23. Crespy V, Morand C, Besson C, Manach C, Demigne C, Remesy C. Quercetin, but not its glycosides, is absorbed from the rat stomach. J Agric Food Chem. 2002;50:618–621. [PubMed]
24. Passamonti S, Vrhovsek U, Vanzo A, Mattivi F. Fast access of some grape pigments to the brain. J Agric Food Chem. 2005;53:7029–7034. [PubMed]
25. Halliwell B, Zhao K, Whiteman M. The gastrointestinal tract: a major site of antioxidant action? Free Radic Res. 2000;33:819–830. [PubMed]
26. Clifford MN. Chlorogenic acids and other cinnamates. Nature, occurence, dietary burden, absorption and metabolism. J Sci Food Agric. 2000;80:1033–1043.
27. Olthof MR, Hollman PC, Katan MB. Chlorogenic acid and caffeic acid are absorbed in humans. J Nutr. 2001;131:66–71. [PubMed]
28. Kuhnau J. The flavonoids. A class of semi-essential food components: their role in human nutrition. World Rev Nutr Diet. 1976;24:117–191. [PubMed]
29. Lee MJ, Maliakal P, Chen L, Meng X, Bondoc FY, et al. Pharmacokinetics of tea catechins after ingestion of green tea and (-)-epigallocatechin-3-gallate by humans: formation of different metabolites and individual variability. Cancer Epidemiol Biomarkers Prev. 2002;11:1025–1032. [PubMed]
30. Falany CN. Enzymology of human cytosolic sulfotransferases. Faseb J. 1997;11:206–216. [PubMed]
31. Spencer JP, Chowrimootoo G, Choudhury R, Debnam ES, Srai SK, Rice-Evans C. The small intestine can both absorb and glucuronidate luminal flavonoids. FEBS Lett. 1999;458:224–230. [PubMed]
32. Hollman PC, Tijburg LB, Yang CS. Bioavailability of flavonoids from tea. Crit Rev Food Sci Nutr. 1997;37:719–738. [PubMed]
33. Dangles O, Dufour C, Manach C, Morand C, Remesy C. Binding of flavonoids to plasma proteins. Methods Enzymol. 2001;335:319–333. [PubMed]
34. Dufour C, Loonis M, Dangles O. Inhibition of the peroxidation of linoleic acid by the flavonoid quercetin within their complex with human serum albumin. Free Radic Biol Med. 2007;43:241–252. [PubMed]
35. Vitrac X, Moni JP, Vercauteren J, Deffieux G, Mérillon JM. Direct liquid chromatography analysis of resveratrol derivatives and flavanonols in wines with absorbance and fluorescence detection. Anal Chim Acta. 2002;458:103–110.
36. Luqman S, Rizvi SI. Protection of lipid peroxidation and carbonyl formation in proteins by capsaicin in human erythrocytes subjected to oxidative stress. Phytother Res. 2006;20:303–306. [PubMed]
37. Pandey KB, Mishra N, Rizvi SI. Protective role of myricetin on markers of oxidative stress in human erythrocytes subjected to oxidative stress. Nat Prod Commun. 2009;4:221–226. [PubMed]
38. Pandey KB, Rizvi SI. Protective effect of resveratrol on markers of oxidative stress in human erythrocytes subjected to in vitro oxidative insult. Phytother Res. 2009. In press. [PubMed]
39. Renaud S, de Lorgeril M. Wine, alcohol, platelets, and the French paradox for coronary heart disease. Lancet. 1992;339:1523–1526. [PubMed]

 

Antioxidants and losing weight, How a high antioxidant diet helps you lose weight

Antioxidants and losing weight, How a high antioxidant diet helps you lose weight

 

Research in progress

 

weight-loss

If you happen to eavesdrop on any conversation about good nutrition, the word antioxidant is bound to come up a few times. Antioxidants are a special kind of micronutrients that prevent harmful chemical reactions caused by oxidation – a chemical reaction that results in the release of destructive elements after the action of oxygen on cells. These elements, known as free radicals, when in abundance, can set off chain reactions that lead to the damage or complete destruction of cells.

 

.Antioxidants are naturally found in many fruits and vegetables, examples include selenium, vitamin C and E and carotenoids. Plants also contain a host of antioxidants and are also rich in phytonutrients which act as antioxidants. These include curcumin in turmeric, resveratrol in red wine and catechins in green tea. The body also naturally produces its own antioxidants such as Glutathione and lipoic acid.

 

While a diet that is rich in antioxidants has numerous benefits, this article will focus on how antibodies increase metabolism, how they block carbs and sugar from being stored as fat and their fat burning action.

 

Although a lot of research has been done on the effects of a high antioxidant diet, they have been inconclusive on their direct effect on weight loss. However, theories have been put out to support this view.

 

Antioxidants are known to turn toxins in the body into harmless elements. Toxins are readily stored in fat cells. Therefore the more toxins we have in our body, the more our bodies will willingly ‘hold on’ to these fat cells in order to prevent toxins from freely roaming in our bodies.  This is usually noticed by people who exercise and reach a plateau in their weight loss curve and in those who have slow metabolism rates. In order to reverse this, a diet rich in antioxidants has been shown to have numerous benefits.

 

Although antioxidants have not been directly linked to fat burning, it is a wonder that people who consume foods rich in antioxidants tend to lose weight. In a study done with overweight participants, those who included green tea in their diet lost more weight compared to the control group. The same has been noted with the intake of water infused with lemon rinds. Lemons and green tea are both very good sources of antioxidants.

 

For fat loss to occur, the body has to convert stored fat into glucose to provide it with energy. Although no conclusive evidence has been found, research suggests that a diet rich in antioxidants can convert your body from a sugar burning to a fat burning machine. This means that instead of using up the sugars you ingest to produce energy, the body will use stored fats. Antioxidants found in green tea have been found to possibly cut through fat stored in the body.

 

More research is yet to be done on the benefits of increasing your intake of antioxidant. However, what is clear is that it is better to take them in their natural form rather than in supplements because foods containing antioxidants have other benefits too.

How high bad cholesterol contributes to aging proccess

How high bad cholesterol contributes to aging proccess

research in progress

 

How High bad Cholesterol Contributes To Aging Process

It is important to note that our bodies need cholesterol to function – only healthy levels. Cholesterol is a fatty substance that is manufactured by the liver and distributed in the body. It enables our bodies to make vitamin D hormones and also makes up bile acids. High cholesterol levels mean that you have more cholesterol in your blood than your body needs to function. Having high cholesterol does not necessarily mean that you have to be overweight or obese. Cholesterol level is simply determined using a blood test.

 

There are two types of cholesterol. High-density lipoprotein (HDL) cholesterol picks up extra cholesterol in your blood stream and redirects it to your liver for repurposing or ejection from the body. Bad cholesterol, low-density lipoprotein cholesterol transport cholesterol to where it may be needed.

How High bad Cholesterol Contributes To Aging Process

Arteries move blood from your heart to the rest of your body. Very high levels of LDL and low levels of HDL can cause your arteries to develop plaque, which is a hardened mixture of fat, cholesterol and other compounds. As the arteries narrow, not enough blood flows to your heart and this may cause a heart attack. Also, reduced blood supply can cause chest discomfort, pain in your joints and back and pressure.

How does this contribute to premature ageing? If you do not have enough energy to move about and you experience pain when you do, chances are that you will not participate in physical activity. There is a direct correlation between exercise and youthfulness. Plaque builds up also interferes with blood flow to your arms and legs making you feel pain or numbness. There is a heightened risk of infection and lack of blood to the tissues may cause tissue death (gangrene)

 

Your skin is very delicate. It has a dense network of tiny veins and arteries under it that supply it with blood and help with the cooling action of the skin. When blood supply s compromised, toxins are not effectively removed from your body and heat cannot be regulated well. Proteins that are required for skin elasticity and tautness are transferred by the blood. If the supply of these proteins is insufficient, the skin looks dull, gets wrinkles and looks darker.

 

Ageing is not only manifested on your skin. It also takes a toll on your brain. Too much bad cholesterol blocks arteries meaning that there is not enough oxygen being supplied to the brain. Brain cells rapidly get damaged and start to die. This can lead to various neurodegenerative conditions that are normally linked to old age.

 

High cholesterol levels can be accompanied by problems of obesity. It is a known fact that when you are overweight, you tend to look older than you really are. The skin is stretched too much and may become flaky and sag.

 

High cholesterol levels in the body can be decreased by leading a healthy lifestyle. Incorporating regular exercise and eating foods that lower cholesterol levels.

How weight loss can help you fight aging

How weight loss can help you fight aging

research in progress

weight loss

 

Obesity I the state of a person being very overweight with a lot of body fat. The common method to calculate obesity is using the Body Mass Index (BMI). It is a measure of how healthy you are given your height and weight. Obesity begins with a BMI score of 30 and above. This is not an absolute calculation and there are other ways of measuring.

 

Obesity, other than causing the obvious physical changes can lead to a several potentially life-threatening conditions. Short term or day-to-day symptoms associated with obesity include breathlessness, snoring, increased sweating, excessive exhaustion over menial tasks, low confidence and self-esteem, difficulty doing any physical activity and a general feeling of isolation. Psychological problems that are linked to obesity have been found to affect relationships with friends and family members. It may also lead to depression.

 

Obesity increases your risk of developing potentially fatal health conditions. These include type 2 diabetes, high blood pressure and cholesterol, asthma, cancer, gallstones, gastro-oesophageal reflux disease, reduced fertility, sleep apnea, liver disease and pregnancy complications. Research has found that obesity reduces your life expectancy by 3 to 10 years.

 

In this article, we will focus on the effect obesity has on ageing. Obesity, as we mentioned above comes with a host of other problems. When too much cholesterol is in the blood, plaque may form in the arteries causing cardiovascular disease such as heart attacks. This is because there is insufficient blood flow in the body. This contributes to ageing because, the skin, being the largest organ, requires adequate blood supply for it to function properly. Proteins responsible for skin elasticity and tautness are transported in the blood. If these are insufficient, the skin becomes saggy, wrinkled and greyish.

 

People suffering from obesity tend to lead fairly sedentary lifestyles. This means that they barely get any exercise done. Exercise helps reduce inflammation that comes with ageing. Inflammation is linked to many chronic illnesses and has been found to be the common factor in many of them. It is also common knowledge that people who are overweight or obese look and feel much older than they actually are. The worst thing about it is that obesity causes a decrease in energy levels in the body and the continued intake of unhealthy foods promotes the burning of sugar instead of fat. This means that people suffering from the disease only get bigger and weaker if they do not make significant lifestyle changes.

 

When a person is overweight or obese, their bones and joints experience a lot of pressure. This makes them brittle and decreases bone density. You can find fairly young people unable to do simple tasks like walking.

 

One of the biggest downfalls of obesity is its degeneration of brain cells. This is caused by a number of factors such as low levels of antioxidants in your diet, constricted blood vessels and a decrease in the production of BDNF. Exercise slows down brain ageing by producing higher BDNF which increases cognitive function.

 

Exercise and resultant weight loss is an inexpensive way to combat the degenerative features of ageing. If you are a beginner, start slow and work your way to higher intensity exercise.

DHA & EPA Antioxidant and anti-aging benefits

DHA & EPA effects and antioxidant benefits!

 

Introducing DHA & EPA:

Omega-3 fatty acids are connected to healthy aging in humans. The omega-3 unsaturated fats derived from fishes, EPA and DHA, have been related with fetal improvement, cardiovascular activities, and Alzheimer’s sickness. Nonetheless, in light of the fact that our bodies don’t proficiently deliver some omega-3 unsaturated fats from marine sources, it is important to get satisfactory sums through fish and fish oil items. The effective and strong antioxidants of EPA and DHA help improving health. They are imperative for appropriate fetal improvement, including neuronal, retinal, and invulnerable function positively and have been connected to provide great outcomes in anticipation, management of weight as well as intellectual capacity in those with exceptionally mellow Alzheimer’s sickness.

Antioxidant Effects of DHA & EPA:

The DHA & EPA supplements have numerous effects on heart. They fight against arrhythmias, heart assault and stroke. They likewise moderate plaque develops, lessen triglycerides, circulatory strain, irritation and thickening, and enhance lipid proportions. Because of their mitigating impacts and strong antioxidants, they might be helpful in treating rheumatoid joint inflammation, asthma and Crohn’s illness. The potential part of DHA & EPA in counteracting and treating osteoporosis, renal disease, cataracts, Alzheimer’s illness, depression and different conditions is as yet being examined.

 

 

Get DHA & EPA for:

For the highest amount of EPA and DHA here is the list of high omega foods by draxe:

  • Mackerel: 6,982 milligrams in 1 cup cooked (174 precent DV)
  • Salmon Fish Oil: 4,767 milligrams in 1 tablespoon (119 percent DV)
  • Cod Liver Oil: 2.664 milligrams in 1 tablespoon (66 percent DV)
  • Walnuts: 2,664 milligrams in 1/4 cup (66 percent DV)
  • Chia Seeds: 2,457 milligrams in 1 tablespoon (61 percent DV)
  • Herring: 1,885 milligrams in 3 ounces (47 percent DV)
  • Salmon (wild-caught): 1,716 milligrams in 3 ounces (42 percent DV)
  • Flaxseeds (ground): 1,597 milligrams in 1 tablespoon (39 percent DV)
  • Tuna: 1,414 milligrams in 3 ounces (35 percent DV)
  • White Fish: 1,363 milligrams in 3 ounces (34 percent DV)
  • Sardines: 1,363 milligrams in 1 can/3.75 ounces (34 percent DV)
  • Hemp Seeds: 1,000 milligrams  in 1 tablespoon (25 percent DV)
  • Anchovies: 951 milligrams in 1 can/2 ounces (23 percent DV)
  • Natto: 428 milligrams in 1/4 cup (10 percent DV)
  • Egg Yolks: 240 milligrams in 1/2 cup (6 percent DV)

 

Antioxidant benefits of DHA & EPA:

 

  • Decrease brain aging and keeps brain healthy: The EPA & DHA supplements are important and might be taken to keep up solid capacity of the mind and retina due to their strong antioxidants. DHA is a building square of tissue in the cerebrum and retina of the eye. It assists in shaping neural transmitters, for example, phosphatidylserine, which is vital for the working of brain. DHA is found in the retina of the eye and taking DHA might be fundamental for keeping the working of eye great.

 

  • Cancer Treatment: Studies revealed that DHA & EPA supplements can avoid and kill different kind of cancers, including colon, breast as well as prostate. While being an effective supplement for cancer patients, at the same time it’s also an effective treatment in those cancer treatments that are done naturally.

 

  • Great for cardiovascular system: EPA and DHA supplements are changed over into substances like hormones known as prostaglandins, and they manage cell action and perfect cardiovascular capacity.

 

  • Diabetes: The strong antioxidants of DHA and EPA can also help in decreasing the danger of diabetic patients from resulting cognitive deficit since it shields the hippocampus cells from being pulverized. Furthermore, they could also help decrease oxidative anxiety, which assumes a great part in the advancement of both micro-vascular and cardiovascular diabetes difficulties.

 

  • Decrease Joint Pains: All the essential antioxidants found in EPA and DHA seem to decrease few joint pains. Human reviews have demonstrated the supplemental fish oil decreases fiery joint pain. They are also successful in diminishing such pain that is brought by joint pain.

 

  • Beneficiary for Human Development: Human development and scholarly advancement – DHA assumes an essential part during the development and improvement of fetal. DHA of the high concentrations are found in the mind and increment 300 to 500 percent in a newborn child’s cerebrum amid the last trimester of pregnancy. Adding DHA supplements in to the pregnant mother’s eating routine might be helpful for the embryo’s mental health. Elderly individuals ought to likewise take EPA DHA, on the grounds that as adults get more established, the bodies frame less EPA and DHA, which may bring about less mental concentration and psychological capacity. Taking some EPA DHA supplements likewise may help with mental variations.

 

  • Decrease muscle degeneration: The strong antioxidants of DHA and EPA diminish the rate of muscle degeneration. A few researches recommends that fit body mass is better held after surgery by expanding the intake of EPA in the eating routine. There are a lot of confirmations proposing that fish oil helps muscle development.

Omega 3 fatty acids, DHA & EPA are naturally found in fishes as well as fish oils. However, DHA & EPA Supplements can also be consumed few times in a week in order to get all the above mentioned benefits.

 

 

Reference Websites:
www.livestrong,com
www.mercola.com

Green Tea, Antioxidant effects and benefits

ALA, ALPHA – LIPOIC ACID, Antioxidant & anti-Inflammatory your body needs

ALA, ALPHA – LIPOIC ACID Antioxidant & anti-Inflammatory 



Other Names for ALPHA – LIPOIC ACID : 
Acetate Replacing Factor, A-Lipoic Acid, Acide Alpha-Lipoïque, Acide Alpha-Lipoïque R, Acide DL-Alpha-Lipoïque, Acide Lipoïque, Acide Thioctique, Acide 1,2-dithiolane-3-pentanoïque


 Introduction to ALPHA – LIPOIC ACID or ALA


Alpha-lipoic acid is a substance made by the body. It is found in every body cell, where it helps turn glucose into energy. Alpha-lipoic acid is a vitamin-like chemical and an antioxidant. ALPHA – LIPOIC ACID or ALA can be found in Yeast, liver, kidney, spinach, broccoli, and potatoes. It is also made in the laboratory for use as medicine.  
Alpha-lipoic acid is used to break down carbohydrates in body and use the energy for organs in the body. Alpha-Lipoic Acid (ALA) is a mitochondrial fatty acid that is highly involved in energy metabolism as mentioned mostly for carbohydrates. ALA has shown benefit against various forms of oxidation and inflammation some part of this is because ALA resets the cycle of vitamin E & C.


ALPHA - LIPOIC ACID

ALA, ALPHA – LIPOIC ACID is Known for:


Alpha-lipoic acid helps prevent certain kinds of cell damage in the body. It also restores vitamin levels such as vitamin E and vitamin C in their cycles so they would work again as an antioxidant in their cycles and this reduces body need of antioxidants. There are some evidence that alpha-lipoic acid can improve the function and conduction of neuron cells in diabetes. ALA antioxidant benefits might also be helpful in liver diseases. 

ALA is know to be used to improve these conditions:

  • Coronary artery bypass graft (CABG) surgery.
  • Diabetes. 
  • Prediabetes. 
  • Diabetic nerve pain. 
  • Vitiligo. 
  • Weight loss. 1800 mg of alpha-lipoic acid daily for 20 weeks.
  • Wound healing. 
  • Alcoholic liver disease. 300 mg of alpha-lipoic acid daily for up to 6 months
  • Alzheimer’s disease. 600-900 mg of alpha-lipoic acid daily for up to 2 years
  • Heart-related nerve problems 
  • Damage to the retina caused by diabetes
  • HIV-related brain problems.
  • Rheumatoid arthritis.  300 mg of alpha-lipoic acid by mouth daily for 12 weeks 



Get ALA for: 


ALA is known to improve the following :

  • Diabetes
  • Cancer
  • Anti-Aging
  • Weight Loss
  • Pain
  • EYE health
  • Nerve Repair
  • Blood Pressure
  • liver disease
  • Heart-related nerve problems
  • Weight loss
  • Cardiovascular 
  • Immune system
  • HIV
  • Inflammatory and pain
  • Neuro-degenerative diseases
  • Cognition decline
  • Autoimmune diseases (rheumatoid arthritis)
  • Joint health
  • Motion Sickness
  • Arthritis
  • Damaging nerves system 
  • Treatment of Dementia
  • Alzheimer’s disease
  • High cholesterol
  • Healthier Arteries




Get ALA naturally:


Main natural sources of ALA ALPHA – LIPOIC ACID

  • Broccoli
  • Spinach
  • Red meat
  • Organ meat (sch as liver, hearts, kidneys from beef or chicken)
  • Brussel sprouts
  • Tomatoes
  • Peas
  • Brewer’s yeast
  • Beets
  • Carrots


ALPHA - LIPOIC ACID



ALA ALPHA – LIPOIC ACID is Both water and fat soluble and found in many natural foods meats, and plants. It can be in a protein bound or in other forms. 
This list is for  lipoyllysinem, the protein-bound form.

Food Dry Weight (mg/g) Protein (ng/g)
1. spinach 3.15 92.51
2. bovine (cow) kidney 2.64 50.57
3. bovine (cow) heart 1.51 41.42
4. broccoli 0.94 41.01
5. tomato 0.56 48.61
6. green pea 0.39 17.13
7. brussel sprouts 0.39 18.39
8. bovine (cow) spleen 0.36 5.69
9. bovine (cow) brain 0.27 4.85
10. rice bran 0.16 4.44






Side Effects of ALA:


  • ALA, Alpha-lipoic acid is known as SAFE by mouth or when applied to the skin. the safe dosage is about the regular dose that can be found in natural sources like plants. 600 or 1200 mg daily.
  • Negative effects could occur with long term high-dosage supplementation. High-dose ALA supplementation is therefore not recommended.
  • People with diabetes should be careful to check their blood sugar levels because alpha-lipoic acid might lower blood sugar.
  • People taking alpha-lipoic acid by mouth might get some rash.
 


Interactions of ALA:

  • Medications for cancer (Chemotherapy) interacts with ALPHA-LIPOIC ACID.
  • Medications for diabetes (Antidiabetes drugs) interacts with ALPHA-LIPOIC ACID
  • Thyroid medications, Levothyroxine — Apha-lipoic acid may lower levels of thyroid hormone. 
  • Vitamin B1 (Thiamine) — Alpha lipoic acid can lower the level of vitamin B1 (Thiamine) in the body. This can be particularly dangerous in alcoholics.












Online sources for this article and good readings on ALA Alpha-lipoic acid:


draxe.com

webmd.com

examine.com

superfoodly.com

umm.edu


List of references and papers:

Androne L, Gavan NA, Veresiu IA, Orasan R. In vivo effect of lipoic acid on lipid peroxidation in patients with diabetic neuropathy. In Vivo. 2000;14(2):327-330.

Beitner H. Randomized, placebo controlled, double-blind study on the clinical efficacy of a cream containing 5% alpha-lipoic acid related to photoaging of facial skin. Br J Dermatol. 2003;149:841-9.

Berkson BM. A conservative triple antioxidant approach to the treatment of hepatitis C. Combination of alpha lipoic acid (thioctic acid), silymarin, and selenium: three case histories. Med Klin. 1999;94 Suppl 3:84-89.

Clark WM, Rinker LG, Lessov NS, Lowery SL, Cipolla MJ. Efficacy of antioxidant therapies in transient focal ischemia in mice. Stroke. 2001;32(4):1000-1004.

Faust A, Burkart V, Ulrich H, et al. Effect of lipoic acid on cyclophosphamide-induced diabetes and insulitis in non-obese diabetic mice. Int J Immunopharmacol. 1994;16:61-66.

Head KA. Natural therapies for ocular disorders, part two: cataracts and glaucoma. Altern Med Rev. 2001;6(2):141-166.

Hruby K, Csomos G, Fuhrmann M, Thaler H. Chemotherapy of Amanita phalloides poisoning with intravenous silibinin. Hum Exp Toxicol. 1983;2(2):183-195.

Ibrahimpasic K. Alpha lipoic acid and glycaemic control in diabetic neuropathies at type 2 diabetes treatment. Med Arh. 2013; 67(1):7-9.

Lynch MA. Lipoic acid confers protection against oxidative injury in non-neuronal and neuronal tissue. Nutr Neurosci. 2001;4(6):419-438.

Melhem MF, Craven PA, Derubertis FR. Effects of dietary supplementation of alpha-lipoic acid on early glomerular injury in diabetes mellitus. J Am Soc Nephrol. 2001;12:124-133.

Melhem MF, Craven PA, Liachenko J, et al. Alpha-lipoic acid attenuates hyperglycemia and prevents glomerular mesangial matrix expansion in diabetes. J Am Soc Nephrol. 2002;13:108-116.

Melmed: Williams Textbook of Endocrinology, 12th ed. Philadelphia, PA: Saunders, An Imprint of Elsevier; 2011.

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Sage, just a mint or strong antioxidants and Anti-Inflammatory