Effective Anti-Aging Treatment | Harvard Researcher Says
Critical step found in DNA repair, cellular aging, Experiments in mice suggest way to thwart DNA damage from aging, radiation
NEW YORK (CBSNewYork) — Would you like to live longer — maybe to 100 in good health?
It just might be possible.
A Harvard researcher said he’s found a safe and effective anti-aging molecule.
Better yet, as CBS2’s Dr. Max Gomez explained, it could also mean treatments for cancer and heart disease.
When most of us think of aging, we think of gray, thinning hair, and plenty of wrinkles.
But when doctors think of anti-aging, they think from the inside — making cells stronger and more vital, which prevents age related diseases, and extends life.
It’s tough to find anyone who doesn’t have at least a few complaints about getting older.
“Getting out of bed, it sounds like a rock band, crack, snap, crackle,” Sean McGoff said.
Now, research led by scientists at Harvard Medical School (HMS) reveals a critical step in a molecular chain of events that allows cells to mend their broken DNA.
The findings, to be published March 24 in Science, offer a critical insight into how and why the body’s ability to fix DNA dwindles over time and point to a previously unknown role for the signaling molecule NAD as a key regulator of protein-to-protein interactions in DNA repair. NAD, identified a century ago, is already known for its role as a controller of cell-damaging oxidation.
Additionally, experiments conducted in mice show that treatment with the NAD precursor NMN mitigates age-related DNA damage and wards off DNA damage from radiation exposure.