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Sugar stands accused | Author makes case for ‘uniquely toxic’ health effects in talk at HLS

Sugar stands accused | Author makes case for ‘uniquely toxic’ health effects in talk at HLS

read th full article about sugar and aging

Science journalist and author Gary Taubes ’77 made his case that sugar consumption — which has risen dramatically over the last century — drives metabolic dysfunction that makes people sick. The hourlong talk was sponsored by the Food Law and Policy Clinic and drawn from Taubes’ new book, “The Case Against Sugar.”

A reputation for “empty calories” — devoid of vitamins and nutrients but otherwise no different from other foods containing an equal number of calories — has allowed sugar to maintain a prominent place in the U.S. diet. Taubes is dubious. First, all calories are not equal because the body metabolizes different foods in different ways. More specifically, there may be something about eating too much sugar — in particular fructose, which is metabolized in the liver — that implicates it in metabolic disease.

“I’m making an argument that sugar is uniquely toxic,” said Taubes. “It has deleterious effects on the human body that lead to obesity and diabetes.”

 

sources

harvard researchers plot early attack against alzheimers

harvard researchers plot early attack against alzheimers

Plotting the demise of Alzheimer’s
New study is major test for power of early action

The Harvard Aging Brain Study, a National Institute on Aging-backed project now in its seventh year, has shown that amyloid beta, the protein thought to cause Alzheimer’s, accumulates in the brain a decade or more before symptoms occur. That finding has given new hope to researchers struggling to move beyond a rash of high-profile Alzheimer’s failures in clinical drug trials. In February, just three months after Eli Lilly & Co. announced a trial failure, drug maker Merck & Co. halted a study. Several additional drugs are still in trials, but researchers are reconsidering their approach and wondering whether the problem is in trying to reverse, rather than prevent, dementia.

Now, the “catch it early” idea is being put to the test in a new study called A4, or Anti-Amyloid Treatment in Asymptomatic Alzheimer’s Disease, led by Sperling and the University of Southern California’s Paul Aisen. Researchers will try an anti-amyloid drug on people who show no signs of cognitive decline, but who do have abnormally high levels of amyloid beta in their brains.

 

Read more on the source

 

 

Alzheimer | What is Aging and is it the same as Alzheimer?

Alzheimer | What is Aging and is it the same as Alzheimer?

Alzheimer

As the years go by, you can expect gradual changes in your body. How your body ages depends partly on your genetics but your lifestyle choices have a greater effect on how well -or not- your body ages.  This brings the question: When does ageing begin? Well, over time, ageing affects the cells of every major organ of your body. In some people, changes can start early and are more visible.

The impact of ageing on our health and function varies in severity. For example, lung tissue starts to lose elasticity around the age of 20 and the muscles of the rib cage slowly begin to shrink. This has led several researchers to say that ageing begins at around 20 years. Some, however, argue that the process begins after the onset of other changes in our bodies caused by puberty at around 12 years.

 

Some of the effects associated with ageing are loss of skin elasticity, thinning of hair, difficulty hearing and seeing, loss of sleep, loss of bone density, slowing down of metabolism, memory changes among others.

Alzheimer

Alzheimer’s disease is a general term for a type of dementia, a condition in which a person develops some cognitive problems resulting from changes in the brain. It is thought to be caused by the buildup of toxins in the brain. At the onset of the disease, people have a hard time remembering recent events, though they might remember past events clearly. With time, the condition deteriorates and other symptoms crop up such as difficulty completing tasks, trouble with words, misplacing things, trouble with visual perception, dramatic mood swings and physical problems.

 

When it comes to brain function, Alzheimer’s and normal ageing are quite similar, only that people with Alzheimer’s disease are just experiencing ageing faster than others. People with Alzheimer’s can forget their loved ones and even how to do simple tasks that they have been doing for years such as feeding themselves and using the toilet.

 

Alzheimer’s disease usually affects people over the age of 65. Someone suffering from the disease may live with it for a few years or even a few decades. While ageing affects both women and men equally – though the signs may show earlier in women, women are more likely to have Alzheimer’s than men. Research shows some evidence that people with high blood pressure and high cholesterol have a higher chance of getting Alzheimer’s. Head injuries, even early in life may also be a cause. However, the most common risks associated with Alzheimer’s are being older and if you have a history of the disease in your family.

 

While normal ageing may take several years for you to experience a noticeable decline in cognitive function, with Alzheimer’s, one you have the disease, people will be able to notice the signs within a couple of months and the curve only goes downward from there. Research shows that a good diet and regular exercise – both physical and mental can slow down the effects of ageing and delay the onset of Alzheimer’s.

Cognitive decline and the best foods used to stop it!

Cognitive decline and the best foods used to stop it!

Antioxidant compounds, contained in fruit, vegetables and tea, have been postulated to have a protective effect against age-related cognitive decline by combating oxidative stress. However, recent research on this subject has been conflicting. here are some basic point about CD and Aging and the main focus of this Article is on foods that Helps us fight CD.

About Cognitive Decline (What is Cognitive Decline?):

If you have Cognitive Decline or cognitive impairment, you may be aware that your memory or mental function has “slipped.” Your family and close friends also may notice a change. But generally these changes aren’t severe enough to significantly interfere with your day-to-day life and usual activities.

When anyone makes some tea or use computer or even read a book, that person it utilizing the cognitive capacities. Cognitive capacities are the mental aptitudes that you have to carry from the easiest to the most perplexing task. These mental abilities incorporate mindfulness, memory, information handling and thinking. As our age increases, the cognitive abilities continuously break down. A specific sum of cognitive decrease is a typical thing in maturing. A few people may encounter an extreme crumbling in psychological abilities, prompting dementia. This can make it difficult to adapt to customary everyday tasks. In order to get rid or avoid such problems, below are some foods that can be utilized.

Mild cognitive impairment may increase your risk of later progressing to dementia, caused by Alzheimer’s disease or other neurological conditions. But some people with mild cognitive impairment never get worse, and a few eventually get better.

 

About Cognitive Decline (What is Cognitive Decline?):

 

Cognitive disorders like CD are a category of mental health disorders that primarily affect learning, memory, perception, and problem solving, and include amnesia, dementia, and delirium. While anxiety disorders, mood disorders, and psychotic disorders can also have an effect on cognitive and memory functions. Cognitive Decline is generally happening to all while aging but we dont really notice that. we get old and our abilities and awareness reduces but we dont understand maybe others do.

Cognitive decline is categorized under dementia in Mental disorders. For dementia cases, studies suggest that diets with high Omega 3 content, low in saturated fats and sugars, along with regular exercise can increase the level of brain plasticity and BDNF. Other studies have shown that mental exercise such a newly developed “computerized brain training programs” can also help build and maintain targeted specific areas of the brain.

Findings from some studies suggest that intakes of vitamin C and E that significantly exceed adequate or recommended intakes (over 130 and 15 mg/day for vitamin C and E, respectively) may be beneficial . This is in slight contrast to a very thorough review of vitamin C, cognitive decline and AD by Harrison , who concluded that a healthy, long-term diet in which adequate vitamin C levels are maintained and vitamin deficiency is avoided may protect against age-related cognitive decline and AD, and be more beneficial than taking supplements. (source & source & Source )

 

About Cognitive Decline (What is Cognitive Decline?):

 

 

Foods that are best to Slow down & stop Cognitive Decline caused by aging:

Green Tea:

Green Tea, Antioxidant effects and benefits

Green tea is on the top of the list in the skin friendly drinks due to its noteworthy storage facility of polyphenols that can cause aging. Having four glasses each day can give amazing results by fighting against aging elements in human body.

 

• GINGER ROOT:

Ginger (root) Unique health benefits & Antioxidant effects

Grated and ground ginger in two wooden spoons ginger root green leaves on the wooden board

Ginger and turmeric are from the same basic family of plants. Health benefits of turmeric is largely mentioned in many articles. But now ginger. Ginger is a Southeast Asian plant. The spice ginger is the underground rhizome of the ginger plant, known botanically as Zingiber officinale. Ginger is used as a spice and medicine.

•  TURMERIC:

Turmeric (Curcumin) Anti-inflammatory & Antioxidant Keeps you young

different types of turmeric barks

Health benefits of turmeric is largely mentioned in many articles. Turmeric is known for improving conditions for arthritis, heartburn (dyspepsia), joint pain, stomach pain, Crohn’s disease and ulcerative colitis, bypass surgery, hemorrhage, diarrhea, intestinal gas, stomach bloating, loss of appetite, stomach ulcers an so on.

•  Sage:

Sage, just a mint or strong antioxidants and Anti-Inflammatory

Sage is an herb, a mint. The leaf is used to make medicine. Sage contains rosmarinic acid, rosmarinic acid is a potent antioxidant and an anti-inflammatory agent. Rosmarinic acid reduces harmful inflammation.

Salmon:

Fish oil, DHA & EPA & OMEGA 3-6-9 Antioxidants and benefits

Raw red fish

Salmon contains astaxanthin which works amazingly on skin and enhances the elasticity of skin by decrease the number of fine lines and wrinkles.  astaxanthin is by some researches considered as the strongest antioxidant ever found.

• Fish and fish oil:

Fish oil, DHA & EPA & OMEGA 3-6-9 Antioxidants and benefits

According to the researchers after several researches, the phenomenal measure of fish they take keeps that away from dangerous heart diseases and cancer. Fish is a copious wellspring of omega-3 fats, which help avert cholesterol development in the arteries and secure against irregular heart rhythms.

•  Olive Oil & Olive extracts:

vitamin-e Unique health benefits & Antioxidant effects

Forty years back, analysts from the Seven Countries Study revealed that the monounsaturated fats found in the olive oil were to a great extent, reason of the low rates of coronary illness and cancer. Presently, the studies  indicated that olive oil additionally contains poly-phenols, effective cancer prevention agents that may help forestall age-related infections.

•  Berries:

Cranberry Strong Antioxidant Effects

All Berries, especially members of some important families, like Rosaceae (strawberry, raspberry, blackberry), and Ericaceae (blueberry, cranberry), belong to the best dietary sources of bioactive compounds (BAC). Because of the antioxidant properties of BAC, they are of great interest also for nutritionists and food technologists due to the opportunity to use BAC as functional foods ingredients. The bioactive compounds in berries contain mainly phenolic compounds (phenolic acids, flavonoids, such as anthocyanins and flavonols, and tannins) and ascorbic acid.

•  MATCHA:

Green Tea, Antioxidant effects and benefits

Matcha is basically green tea leaves that have been stone ground and processed into a powder. The powder is then filtered and raced with boiling water. Due to the difficult procedure required to deliver matcha, the tea is for the most part expensive than others.

OLIVE LEAF

branch of green olives antioxidant benefits

branch of green olives

If you are going to consider getting Olive leaf (extracts) you should know based on the studies these are the situations that it has been proven that Olive leaf (extracts) can improve.
Lowers Blood Pressure, Improves Cardiovascular Health, Diabetes, Reduces the Risk of Cancer and so on.

 

• Eggs:

Protein (amino acids) repairs all those cells that have endured the damage from free radical. Eggs, an amazing source of protein, likewise contain biotin which is an essential vitamin that protect the body from free radicals.

• Pomegranate:

The antioxidant rich fruit may help skin to make more collagen and can also help in speeding healing. The essential nutrients in it help making the skin look fresh and glower and it works amazingly as an anti aging food.

• Beans:

Beans are another protein source. They help repair cells that have endured the free radical damage. During digestion, protein separates into amino acids, the building squares of cells which further help to speed as well as repair and regenerate the skin cells along with collagen.

• Chocolate coco powder:

If dietary phenolics are active in-vivo antioxidants, chocolate can contribute a significant portion of dietary antioxidants, and the pleasant pairing of red wine and dark chocolate could have synergistic advantages beyond their complementary tastes. According to a study, the people who live in Kuna in the San Blas islands near panama, have a rate of heart illness that is a great percent less than those of Panamanians. The Kuna people, in order to stay away from heart diseases, drink a lot of a refreshments made with liberal extents of chocolate, which is bizarrely rich in flavanols that help protect the sound capacity of veins. Keeping up young veins and fights aging.

•  Watermelon:

The reviving and sweet treat contains a definitive cancer prevention agent, vitamin C, in addition to lycopene as well as potassium, which controls the adjust of water and supplements in cells and makes individuals look healthy and young.

• Dark Chocolate:

The sweet chocolate is rich in cocoa flavanols, plant compounds as well as the effective & strong antioxidant properties, which help hydrate skin and enhance circulation.

• Walnuts:

It’s the only kind of nut that contains a significant amount of unsaturated fats, which is particularly important for vegetarians who are not able to eat fish. Walnuts pack an omega-3 called alpha-linolenic corrosive. Deficiency in this fat can bring about dermatitis, which is related with dry, flaky skin. So, having walnuts will make the skin fresh, and young.

• Citrus fruits peel:

Analysts from the University of Arizona took a gander at individuals who stated that they ate citrus fruits, squeezes, and peels each week. Individuals, who ate peels such as orange peel or lemon juice, had a 33% diminished hazard for “squamous cell carcinoma”. Juices and fruit didn’t have any impact. Limonene is a compound found in the oil in the peels that offers the UV-defensive benefits and makes the skin look great.

• Walnuts:

Walnuts are stuffed with healthy as well as anti inflammatory supplements, and are the main great nut source of alpha linolenic corrosive. They help advance blood stream, which thusly takes into consideration a great delivery of oxygen to the cerebrum. What’s more, a study found that mice with the infection that were routinely nourished walnuts had enhanced memory, learning and function ability coordination.

• Coffee:

Caffeine, the gentle stimulant found in coffee actually enhances mental acuity. Beside caffeine’s mind boosting impacts, caffeine’s cell reinforcement lavishness keeps up the mental health. Also, some exploration recommends that drinking coffee can really fight with depression and anxiety in ladies and can stop cognitive decline.

• Blueberries:

Incredible things do come in little bundles, blueberries are a natural product few attempt to eat each and every. That is on the grounds that they have such a variety of extraordinary medical advantage ­while having an aftertaste like a great treat. It’s one of the most astounding cell reinforcement rich sustenance known to man, including vitamin C and vitamin K and fiber. As a result of their elevated amounts of Gallic acid, blueberries are particularly great at shielding our brains from degeneration, stress and cognitive decline.

• Broccoli:

It’s one of the best foods to improve brain health. On account of its elevated amounts of vitamin K and choline, it will help keep your memory sharp.

• Coconut oil:

It is a standout among the most flexible and bravo nourishments for brains out there. With 77 coconut oil uses and cures, there’s nothing that coconut oil can’t help. What’s more, with regards to your mental health it’s loaded with other advantages, as well. Coconut oil functions as a characteristic calming, stifling cells in charge of aggravation. It can help with memory misfortune as a person becomes older and kills terrible microbes that hang out in the guts. Hence, it’s great to stop cognitive decline in human.

• Egg Yolks:

Egg yolks contain a lot of choline, which helps in fetal mental health for pregnant ladies. It additionally separates bethane, a synthetic that produces hormones identified with bliss and fight against cognitive decline. The eggs can really make an individual happy and keep the mental health great.

• Spinach:

Spinach is rich in antioxidants, which is thought to fight against cognitive decline. What’s more, a study found that ladies who revealed eating the most verdant green and cruciferous vegetables had an especially decreased rate of cognitive decline as contrasted with the individuals who ate the minimum.

• Tomatoes:

A study found that lycopene-rich tomato helped participants prevent sunburn when they combined it with olive oil and use it for ten weeks without missing any day. Other than being an extraordinary source of strong antioxidant lycopene, tomatoes are considered a high carotenoid fruit. These nutrients may help to get rid from free radicals that can cause many diseases including aging.

 

 

 

Some good sources for cognition Decline:

http://www.mayoclinic.org/diseases-conditions/mild-cognitive-impairment/home/ovc-20206082

https://link.springer.com/article/10.1007%2Fs11130-013-0370-0

https://en.wikipedia.org/wiki/Cognitive_disorder

 

cranberry strong antioxidant effects, benefits and sideffects

ALA, ALPHA – LIPOIC ACID, Antioxidant & anti-Inflammatory your body needs

ALA, ALPHA – LIPOIC ACID Antioxidant & anti-Inflammatory 



Other Names for ALPHA – LIPOIC ACID : 
Acetate Replacing Factor, A-Lipoic Acid, Acide Alpha-Lipoïque, Acide Alpha-Lipoïque R, Acide DL-Alpha-Lipoïque, Acide Lipoïque, Acide Thioctique, Acide 1,2-dithiolane-3-pentanoïque


 Introduction to ALPHA – LIPOIC ACID or ALA


Alpha-lipoic acid is a substance made by the body. It is found in every body cell, where it helps turn glucose into energy. Alpha-lipoic acid is a vitamin-like chemical and an antioxidant. ALPHA – LIPOIC ACID or ALA can be found in Yeast, liver, kidney, spinach, broccoli, and potatoes. It is also made in the laboratory for use as medicine.  
Alpha-lipoic acid is used to break down carbohydrates in body and use the energy for organs in the body. Alpha-Lipoic Acid (ALA) is a mitochondrial fatty acid that is highly involved in energy metabolism as mentioned mostly for carbohydrates. ALA has shown benefit against various forms of oxidation and inflammation some part of this is because ALA resets the cycle of vitamin E & C.


ALPHA - LIPOIC ACID

ALA, ALPHA – LIPOIC ACID is Known for:


Alpha-lipoic acid helps prevent certain kinds of cell damage in the body. It also restores vitamin levels such as vitamin E and vitamin C in their cycles so they would work again as an antioxidant in their cycles and this reduces body need of antioxidants. There are some evidence that alpha-lipoic acid can improve the function and conduction of neuron cells in diabetes. ALA antioxidant benefits might also be helpful in liver diseases. 

ALA is know to be used to improve these conditions:

  • Coronary artery bypass graft (CABG) surgery.
  • Diabetes. 
  • Prediabetes. 
  • Diabetic nerve pain. 
  • Vitiligo. 
  • Weight loss. 1800 mg of alpha-lipoic acid daily for 20 weeks.
  • Wound healing. 
  • Alcoholic liver disease. 300 mg of alpha-lipoic acid daily for up to 6 months
  • Alzheimer’s disease. 600-900 mg of alpha-lipoic acid daily for up to 2 years
  • Heart-related nerve problems 
  • Damage to the retina caused by diabetes
  • HIV-related brain problems.
  • Rheumatoid arthritis.  300 mg of alpha-lipoic acid by mouth daily for 12 weeks 



Get ALA for: 


ALA is known to improve the following :

  • Diabetes
  • Cancer
  • Anti-Aging
  • Weight Loss
  • Pain
  • EYE health
  • Nerve Repair
  • Blood Pressure
  • liver disease
  • Heart-related nerve problems
  • Weight loss
  • Cardiovascular 
  • Immune system
  • HIV
  • Inflammatory and pain
  • Neuro-degenerative diseases
  • Cognition decline
  • Autoimmune diseases (rheumatoid arthritis)
  • Joint health
  • Motion Sickness
  • Arthritis
  • Damaging nerves system 
  • Treatment of Dementia
  • Alzheimer’s disease
  • High cholesterol
  • Healthier Arteries




Get ALA naturally:


Main natural sources of ALA ALPHA – LIPOIC ACID

  • Broccoli
  • Spinach
  • Red meat
  • Organ meat (sch as liver, hearts, kidneys from beef or chicken)
  • Brussel sprouts
  • Tomatoes
  • Peas
  • Brewer’s yeast
  • Beets
  • Carrots


ALPHA - LIPOIC ACID



ALA ALPHA – LIPOIC ACID is Both water and fat soluble and found in many natural foods meats, and plants. It can be in a protein bound or in other forms. 
This list is for  lipoyllysinem, the protein-bound form.

Food Dry Weight (mg/g) Protein (ng/g)
1. spinach 3.15 92.51
2. bovine (cow) kidney 2.64 50.57
3. bovine (cow) heart 1.51 41.42
4. broccoli 0.94 41.01
5. tomato 0.56 48.61
6. green pea 0.39 17.13
7. brussel sprouts 0.39 18.39
8. bovine (cow) spleen 0.36 5.69
9. bovine (cow) brain 0.27 4.85
10. rice bran 0.16 4.44






Side Effects of ALA:


  • ALA, Alpha-lipoic acid is known as SAFE by mouth or when applied to the skin. the safe dosage is about the regular dose that can be found in natural sources like plants. 600 or 1200 mg daily.
  • Negative effects could occur with long term high-dosage supplementation. High-dose ALA supplementation is therefore not recommended.
  • People with diabetes should be careful to check their blood sugar levels because alpha-lipoic acid might lower blood sugar.
  • People taking alpha-lipoic acid by mouth might get some rash.
 


Interactions of ALA:

  • Medications for cancer (Chemotherapy) interacts with ALPHA-LIPOIC ACID.
  • Medications for diabetes (Antidiabetes drugs) interacts with ALPHA-LIPOIC ACID
  • Thyroid medications, Levothyroxine — Apha-lipoic acid may lower levels of thyroid hormone. 
  • Vitamin B1 (Thiamine) — Alpha lipoic acid can lower the level of vitamin B1 (Thiamine) in the body. This can be particularly dangerous in alcoholics.












Online sources for this article and good readings on ALA Alpha-lipoic acid:


draxe.com

webmd.com

examine.com

superfoodly.com

umm.edu


List of references and papers:

Androne L, Gavan NA, Veresiu IA, Orasan R. In vivo effect of lipoic acid on lipid peroxidation in patients with diabetic neuropathy. In Vivo. 2000;14(2):327-330.

Beitner H. Randomized, placebo controlled, double-blind study on the clinical efficacy of a cream containing 5% alpha-lipoic acid related to photoaging of facial skin. Br J Dermatol. 2003;149:841-9.

Berkson BM. A conservative triple antioxidant approach to the treatment of hepatitis C. Combination of alpha lipoic acid (thioctic acid), silymarin, and selenium: three case histories. Med Klin. 1999;94 Suppl 3:84-89.

Clark WM, Rinker LG, Lessov NS, Lowery SL, Cipolla MJ. Efficacy of antioxidant therapies in transient focal ischemia in mice. Stroke. 2001;32(4):1000-1004.

Faust A, Burkart V, Ulrich H, et al. Effect of lipoic acid on cyclophosphamide-induced diabetes and insulitis in non-obese diabetic mice. Int J Immunopharmacol. 1994;16:61-66.

Head KA. Natural therapies for ocular disorders, part two: cataracts and glaucoma. Altern Med Rev. 2001;6(2):141-166.

Hruby K, Csomos G, Fuhrmann M, Thaler H. Chemotherapy of Amanita phalloides poisoning with intravenous silibinin. Hum Exp Toxicol. 1983;2(2):183-195.

Ibrahimpasic K. Alpha lipoic acid and glycaemic control in diabetic neuropathies at type 2 diabetes treatment. Med Arh. 2013; 67(1):7-9.

Lynch MA. Lipoic acid confers protection against oxidative injury in non-neuronal and neuronal tissue. Nutr Neurosci. 2001;4(6):419-438.

Melhem MF, Craven PA, Derubertis FR. Effects of dietary supplementation of alpha-lipoic acid on early glomerular injury in diabetes mellitus. J Am Soc Nephrol. 2001;12:124-133.

Melhem MF, Craven PA, Liachenko J, et al. Alpha-lipoic acid attenuates hyperglycemia and prevents glomerular mesangial matrix expansion in diabetes. J Am Soc Nephrol. 2002;13:108-116.

Melmed: Williams Textbook of Endocrinology, 12th ed. Philadelphia, PA: Saunders, An Imprint of Elsevier; 2011.

Mitkov MD, Aleksandrova IY, Orbetzova MM. Effect of transdermal testosterone or alpha-lipoic acid on erectile dysfunction and quality of life in patients with type 2 diabetes mellitus. Folia Med (Plovdiv). 2013; 55(1):55-63.

Monograph:Alpha-Lipoic Acid. Altern Med Rev. 1998;3(4):308-311.

Nagamatsu M, Nickander KK, Schmelzer JD,et al. Lipoic acid improves nerve blood flow, reduces oxidative stress, and improves distal nerve conduction in experimental diabetic neuropathy. Diabetes Care. 1995;18:1160-1167.

Packer L, Kraemer K, Rimbach G. Molecular aspects of lipoic acid in the prevention of diabetes complications. Nutrition. 2001;17(10):888-895.

Packer L, Tritschler HJ, Wessel K. Neuroprotection by the metabolic antioxidant alpha-linoic acis. Free Radic Biol Med. 1997;22:359-378.

Packer L, Witt EH, Tritschler HJ. Alpha-lipoic acid as a biological antioxidant. Free Rad Bio Med. 1995;19(2):227-250.

Panigrahi M, Sadguna Y, Shivakumar BR, Kolluri SV, Roy S, Packer L, Ravindranath V. Alpha-Lipoic acid protects against reperfusion injury following cerebral ischemia in rats. Brain Res. 1996;717(1-2):184-188.

Rakel D. Rakel Integrative Medicine, 3rd ed. Philadelphia, PA: Saunders, An Imprint of Elsevier; 2012.

Segermann J, Hotze A, Ulrich H, et al. Effect of alpha-lipoic acid on the peripheral conversion of thyroxine to triiodothyronine and on serum lipid-, protein- and glucose levels. Arzneimittelforschung. 1991;41:1294-1298.

Xu J, Gao H, Song L, et al. Flaxseed oil and alpha-lipoic acid combination ameliorates hepatic oxidative stress and lipid accumulation in comparison to lard. Lipids Health Dis. 2013; 12:58.

Yoo TH, Lee JH, Chun HS, Chi SG. a-Lipoic acid prevents p53 degradation in colon cancer cells by blocking NF-kB induction of RPS6KA4. Anticancer Drugs. 2013; 24(6):555-65.

Ziegler D, Ametov A, Barinov A, et al. Oral treatment with alpha-lipoic acid improves symptomatic diabetic polyneuropathy: The SYDNEY 2 trial. Diabetes Care. 2006;29:2365-70.

Ziegler D, Gries FA. Alpha-lipoic acid in the treatment of diabetic peripheral and cardiac autonomic neuropathy. Diabetes. 1997;46 (suppl 2):S62-66.

Ziegler D, Reljanovic M, Mehnert H, Gries FA. Alpha-lipoic acid in the treatment of diabetic polyneuropathy in Germany: current evidence from clinical trials. Exp Clin Endocrinol Diabetes. 1999; 107:421-430.


Turmeric (Curcumin) Anti-inflammatory & Antioxidant Keeps you young

Sage, just a mint or strong antioxidants and Anti-Inflammatory