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DOES SUGAR MAKE YOU AGE FASTER IN ANY WAY?

DOES SUGAR MAKE YOU AGE FASTER IN ANY WAY?

We love sugar, dont we? well there is a reason for that. Sugar tastes sweet right? That also has a reason. We cant get enough sugar and we love it because energy and good fuel matters to hour body and system of perception. Sugar brings you the best fast burning fuel. so We all love it. But aside from the fast burning benefit that does not perfectly fit to our new modern life style, what downsides does it have for our body? We used to get a sugary thing eat it an ruu…uun. In our old lifestyle it helped you run and dont run out of energy and there is no doubt about that.

read the full article about sugar and aging

sugar aging

DOES SUGAR LEAD YOUR BODY TO A FAST TRACK AGING?

Research shows that excess intake of processed sugar in your diet can cause wrinkles. Dark circles, dehydration of the skin and can increase the rate of ageing. Sugar can be found naturally in about everything you eat, such like in fruit and vegetables. Foods such as cakes, biscuits and soda have very high amounts of processed sugar. Sugar comes in different forms and each of them is processed differently by our bodies. Fructose, for example, will make you pack on pounds faster when ingested when compared to glucose.

What is brain plasticity? What is Brain BDNF?

What is brain plasticity? What is  BDNF?

BRAIN BDNF (BRAIN PLASTICITY) AND EXERCISE

 

What is brain plasticity? Neuroplasticity – or brain plasticity – is the ability of the brain to modify its connections or re-wire itself. Without this ability, any brain, not just the human brain, would be unable to develop from infancy through to adulthood or recover from brain injury.

What is  BDNF?   The BDNF gene provides instructions for making a protein found in the brain and spinal cord called brain-derived neurotrophic factor. This protein promotes the survival of nerve cells (neurons) by playing a role in the growth, maturation (differentiation), and maintenance of these cells. In the brain, the BDNF protein is active at the connections between nerve cells (synapses), where cell-to-cell communication occurs. The synapses can change and adapt over time in response to experience, a characteristic called synaptic plasticity. The BDNF protein helps regulate synaptic plasticity, which is important for learning and memory.

The BDNF protein is found in regions of the brain that control eating, drinking, and body weight; the protein likely contributes to the management of these functions. read more about exercise and brain bdnf

 

Read more about antioxidants

 

 

Related questions:

What are antioxidants in green tea?

Green tea substance with antioxidant benefits?

Is all tea types the same in antioxidants?

The strongest tea in antioxidants?

Is green tea beneficial?

What are green tea health benefits?

 

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Read more about antioxidants

Read More about Anti aging

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Keywords: Green tea catechins, dyslipidemia, oxidative stress, inflammation, endothelial cells, platelets, proliferation, cardiovascular disease

CAN YOU GROW NEW BRAIN CELLS?

CAN YOU GROW NEW BRAIN CELLS?

 

The science of neurogenesis suggests it’s possible to create neurons that improve your memory and thinking skills.(source)  For example in relation of AHN and exercise in a study Named: Physical exercise increases adult hippocampal neurogenesis in male rats provided it is aerobic and sustained  done by Miriam S. Nokia, Department of Psychology, University of Jyväskylä, Finland. On Exercise and AHN it was found that: Adult hippocampal neurogenesis is a continuous process that contributes to a variety of adaptive behaviours, such as learning (for review, see Aimone et al. 2014). A well-demonstrated means of promoting AHN in rodents is aerobic exercise, namely running (van Praag et al. 1999). High-intensity interval training had a smaller than expected effect on AHN. Resistance training does not promote AHN. read more

 

Read more about antioxidants

Read More about Cancer

 

 

Related questions:

What are antioxidants in green tea?

Green tea substance with antioxidant benefits?

Is all tea types the same in antioxidants?

The strongest tea in antioxidants?

Is green tea beneficial?

What are green tea health benefits?

 

………………………………………………………………………………………………

Read more about antioxidants

Read More about Anti aging

……………………………………………………………………………………………..

Please Leave follow up questions in the comment section

Source

Keywords: Green tea catechins, dyslipidemia, oxidative stress, inflammation, endothelial cells, platelets, proliferation, cardiovascular disease

Anti aging Antioxidant rich foods and Exercise, two Most effective factors of anti-aging lifestyle

Anti aging Antioxidant rich foods and Exercise

Two Most effective factors of anti-aging lifestyle

lose-weight anti aging antioxidants

What is aging and what is anti-aging?

You know aging is happening when you see the traces of it in your skin, joints and face. But have ever gone a bit deeper to know Why do we age? Is it normal? What makes aging an acceptable norm? Can it change?
Many say you cannot really stop body from aging and its fate and the nature of how it behaves. And some others say aging is a disease and can be cured. But to be honest the truth is somewhere between those lines. It happens because our DNA is designed to be destructed in some certain situations. Free radicals in our cells and outside our cells are always destructing other molecules, basically because they are unstable forms of molecules. Free radicals interact with other molecules in the body as they are in blood and metabolism, they cause Oxidative Damage. Sources of oxidative damage can be inflammations inside our body or sources from outside like:

• Smoking (first or second hand)
• Excessive exposure to UV rays
• Air Pollution
• Eating an unhealthy diet
• Certain medications and/or treatments
• Excessive exercise or physical activities

 

Antioxidants Counteract Oxidative Stress and Free Radicals

Antioxidants that you have probably heard of them are important players in this game. Antioxidant foods or some may say Anti-aging foods are the one that are rich in anti-oxygen agents which we call antioxidant agents. The main thing that antioxidants do that help us with an anti-aging lifestyle is that they fight against the free radicals. Usually when free radicals quantity is more that antioxidants the aging goes faster and faster.
Our body knows what the main molecules are that it is in war with, the free radicals. And the strongest and the best antioxidants are made inside our body that are hundreds of times more effective than foods. Foods are mostly effective in the inside cell fight and the antioxidants from foods are mostly effective and working on outside cell fights against free radicals.

 

lose-weight anti aging antioxidants

So the main two ways and factors to have a healthy anti-aging lifestyle is
1. To activate and trigger the antioxidants made by our body
2. To eat best antioxidant foods and (also skip the sugar…)

Activating the antioxidants within you

For triggering the intra antioxidants made in our body like glutathione which is the strongest antioxidant, exercise has been proven over and over that is the main thing that increase both brain BDNF and glutathione levels in our body. But not any sort of exercise. The most effective type that can actually make your body increase intra-antioxidants is intense exercise or HIIT: High intensity interval training. HIT intense interval training can increase bdnf. Yes, Intense Exercise is number 1. If you don’t exercise much, your brain may not be producing sufficient BDNF. To increase it, you’ll want to engage in an intense exercise; the greater the intensity, the more likely BDNF production will increase.

Both are some of the most important aging factors. Exercise Increases Brain plasticity and memory that leads to better learning. Brain plasticity is the main factor of brain aging. Basically plasticity means your brain has the capability of learning or not. Glutathione is also triggered by some foods like ginger and turmeric root but.

 

lose-weight anti aging antioxidants

Antioxidant foods in your diet

For The healthy foods and a diet full of antioxidant foods you should include some spices and foods in your diet like ginger, turmeric, clove and also eat some fruits daily like blueberries, cranberries, and acai berries.  Many other activities and strategies are associated with anti-aging lifestyle but the main two ones that can really lift up your mood and prevent fast aging and even stop it to some degrees are as mentioned Exercise and Antioxidant rich foods.

Strongest Anti-aging Antioxidant foods & supplements, list, rank

Strongest Antioxidant foods & supplements & herbs

Best antioxidant foods natural anti aging

Best strong antioxidant foods rank list

Antioxidants are molecular agents that fight against the free radicals. they are made internally by our body but also and consumed externally by foods. When antioxidants are less than free-radicals aging goes very fast and out body destructs. When antioxidants are more than free radicals the aging process slows down and you feel much better in terms of metabolism and healthiness. Antioxidants are our body anti-aging agents.

Strongest Antioxidant foods top list

  1. Goji berries25,000 ORAC score
  2. Wild blueberries14,000 ORAC score
  3. Dark chocolate21,000 ORAC score
  4. Pecans: 17,000 ORAC score
  5. Artichoke: 9,400 ORAC score
  6. Elderberries: 14,000 ORAC score
  7. Kidney beans8,400 ORAC score
  8. Cranberries9,500 ORAC score
  9. Blackberries5,300 ORAC score
  10. Cilantro: 5,100 ORAC score

 

 

The best antioxidants Between Herbs rank

  1. Clove:314,446 ORAC score
  2. Cinnamon: 267,537 ORAC score
  3. Oregano: 159,277 ORAC score
  4. Turmeric102,700 ORAC score
  5. Cocoa80,933 ORAC score
  6. Cumin: 76,800 ORAC score
  7. Parsley (dried)74,349 ORAC score
  8. Basil67,553 ORAC score
  9. Ginger: 28,811 ORAC score
  10. Thyme27,426 ORAC score

 

The Strongest antioxidants supplements list

  1. Glutathione
  2. Quercetin
  3. Lutein
  4. Vitamin C
  5. Resveratrol
  6. Astaxanthin
  7. Selenium
  8. Lavender Essential Oil
  9. Chlorophyll
  10. Frankincense Essential Oil

 

 

Sugar stands accused | Author makes case for ‘uniquely toxic’ health effects in talk at HLS

Sugar stands accused | Author makes case for ‘uniquely toxic’ health effects in talk at HLS

read th full article about sugar and aging

Science journalist and author Gary Taubes ’77 made his case that sugar consumption — which has risen dramatically over the last century — drives metabolic dysfunction that makes people sick. The hourlong talk was sponsored by the Food Law and Policy Clinic and drawn from Taubes’ new book, “The Case Against Sugar.”

A reputation for “empty calories” — devoid of vitamins and nutrients but otherwise no different from other foods containing an equal number of calories — has allowed sugar to maintain a prominent place in the U.S. diet. Taubes is dubious. First, all calories are not equal because the body metabolizes different foods in different ways. More specifically, there may be something about eating too much sugar — in particular fructose, which is metabolized in the liver — that implicates it in metabolic disease.

“I’m making an argument that sugar is uniquely toxic,” said Taubes. “It has deleterious effects on the human body that lead to obesity and diabetes.”

 

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Exercise and Aging | Intense exercise can stop or slow down Aging

Exercise and Aging | Intense exercise can stop or slow down Aging

Before we start….. Exercise is the Most important thing we can do against aging. read more.

How exercise slows down aging?

  • Exercise Increases Brain plasticity and memory that leads to better learning
  • Exercise Increases brain BDNF
  • Exercise Boosts and improves cardiovascular system 
  • Exercise creates inflammations that makes body boost immune system
  • Exercise triggers body production of growth Hormone
  • Exercise triggers body sweat system 
  • Exercise fights obesity 
  • Triggers production of new brain cells

 

Research in progress

 

Main question on exercise-aging relation:

Before going into details of how exercise can actually improve your body we should have  and understand some questions:

 

  • Why do we HAVE TO exercise?
  • Do you know what it means that cells in our body and specially our brain Age?
  • Does our body make new cells everywhere? even in brain?
  • When does aging stats?
  • Do you know Why our body operates the way it does and how can it affect our modern lifestyle?
  • Does aging happen in brain or skin or all of our body?
  • If we are perceiving the world in our brain shouldn’t we really care about protecting it from getting old?

 

First Aging starts From 15 to 20 so take this seriously. If you are in your 20s, you are already there.

We are based on our needs. All body structure and how it functions is designed or evolved based on its needs. if we did not need a hand we would not have one or hair or nose. The structure of our body is designed to get stronger and grow under pressure of need. fear is one of the strongest tools in nature that makes animals shape the way they are.

Telomeres that are the tiny caps found on the end of DNA strands, like plastic aglets on shoelaces. They are believed to protect the DNA from damage during cell division and replication. As a cell ages, its telomeres naturally shorten and fray. our modern lifestyle expedites that things like smoking or bad foods or obesity all contribute hugely to expediting that process.

In our original lifestyle we used to run to hunt or escape, for food and staying alive and keep living. our cells and DNA knows why they are shaped the way they are. Actually exercise and intense physical activity has been an integral part of our lives in the past. and our structure is shaped based on that.

If we dont use part of our body it starts weakening to its minimum. Imaging your muscles if you dont use a specific muscle it weakens even if you are an athlete if you stop the pressure after a while you see that because your muscle is not under pressure it loosens up and weakens. after one or two years you are nothing like your old body  and that strong part is the weakest. you did nothing and that is the exact problem. doing nothing with your body for your DNA means you dont need it. so it gets rid of it. It can not get rid of it in one generation but weakens it as its possible. and eventually gets rid of it if you pass enough generations.

Remember it should be intense and/or long. The high intensity and long time is what makes the difference and makes your body to fight aging.  

High intensity exercise is a strong signal to all cells involved specially your brain to work and grow and get stronger.Also long time can do it in another way for sure a 40 min session is much better and more effective than a 10 min session. you body feels like its running out of resources and power. They are all feeling fear and that is what is running them forward. Because that is how our body made to survive if it feels loos for a long time it means aging and slow death.

 

 

Aging In our brain and memory vs exercise | Can you grow new brain cells?

The science of neurogenesis suggests it’s possible to create neurons that improve your memory and thinking skills.(source)  For example in relation of AHN and exercise in a study Named: Physical exercise increases adult hippocampal neurogenesis in male rats provided it is aerobic and sustained  done by Miriam S. Nokia, Department of Psychology, University of Jyväskylä, Finland. On Exercise and AHN it was found that: Adult hippocampal neurogenesis is a continuous process that contributes to a variety of adaptive behaviours, such as learning (for review, see Aimone et al. 2014). A well-demonstrated means of promoting AHN in rodents is aerobic exercise, namely running (van Praag et al. 1999). High-intensity interval training had a smaller than expected effect on AHN. Resistance training does not promote AHN.

In accordance with several previous reports on the beneficial effects of running on AHN and cognition in rodents (for a review, see Vivar et al. 2013), in our present study forced endurance training on a treadmill as well as voluntary running in a running wheel led to a higher number of immature adult-born hippocampal neurons compared with that observed in animals not engaged in aerobic exercise. Furthermore, we found that daily voluntary running on a running wheel increased AHN considerably more than 30 min of forced endurance training on a treadmill three times a week. The correlation between running distance and AHN might be explained by considering the consequences of running (in a more naturalistic setting). The further an individual travels, the more likely it is to encounter new environments and stimuli from which it must make sense rapidly.

 

 

Finally in the  Conclusion it is mentioned that: Sustained aerobic exercise increases AHN and advances this field of study in several ways. First, we tested several different forms of physical exercise to study their effects on AHN. We also took advantage of a newly developed genetically heterogeneous contrasting rat model system that we selectively bred for low and high response to aerobic training to take into account genetic variation in training responsiveness. According to our findings, anaerobic resistance training does not affect AHN in the studied animals, despite its overall positive effects on physical fitness. Second, the effects of exercise on AHN depend, at least to some extent, on sustained aerobic activity, as HIT did not have statistically significant effect on AHN. Third, the highest numbers of adult-born hippocampal neurons were observed in rats selectively bred for a high response to aerobic exercise that ran voluntarily on running wheels. Thus, for all reasons combined, AHN is highest in animals born with a tendency for a higher response to exercise training ,engaging in a large amount of voluntary aerobic activity. (source)

 

 

Why and how physical activity promotes experience-induced brain plasticity is also another important study done by  Gerd Kempermann , from Center for Regenerative Therapies Dresden, German Research Foundation, Dresden, Germany.

In animals, most if not all aspects of cognition are inseparable from locomotion and physical activity. Exploration, spatial navigation, and most types of learning accessible in a rodent are based on its movement in the outer world. Search for food, shelter, and mates are physical activities, requiring mental input to be successful on both a phylogenetic and ontogenetic scale. Consequently, the fact that running induces neurogenesis will be less counterintuitive if one appreciates physical activity as a basis for cognition. An important question is, whether this association is preserved in humans. Physical activity would be an intrinsic behavior-based signal to the brain (and hippocampus) implying that the likelihood of cognitive challenge is increased. In addition, one could speculate that running long distances increases the chance to encounter new environments increasing the need for spatial orientation and memory like wild animals that need to find the way back to their safe shelter. (source)

 

 

 

Brain BDNF (Brain plasticity) and Exercise

What is brain plasticity? Neuroplasticity – or brain plasticity – is the ability of the brain to modify its connections or re-wire itself. Without this ability, any brain, not just the human brain, would be unable to develop from infancy through to adulthood or recover from brain injury.

What is  BDNF?   The BDNF gene provides instructions for making a protein found in the brain and spinal cord called brain-derived neurotrophic factor. This protein promotes the survival of nerve cells (neurons) by playing a role in the growth, maturation (differentiation), and maintenance of these cells. In the brain, the BDNF protein is active at the connections between nerve cells (synapses), where cell-to-cell communication occurs. The synapses can change and adapt over time in response to experience, a characteristic called synaptic plasticity. The BDNF protein helps regulate synaptic plasticity, which is important for learning and memory.

The BDNF protein is found in regions of the brain that control eating, drinking, and body weight; the protein likely contributes to the management of these functions.

Pushup for both your muscles and your brain.

 

How To Increase BDNF (Brain-Derived Neutrophic Factor)

Increase your BDNF , there are some specific ways this can be done. It should also be noted that many methods that increase BDNF simultaneously increase neurogenesis.

 

 

1. Intense Exercise

Yes, Intense Exercise is number 1. If you don’t exercise much, your brain may not be producing sufficient BDNF. To increase it, you’ll want to engage in an intense exercise; the greater the intensity, the more likely BDNF production will increase. It has also been suggested that the more frequently you engage in high intensity exercise, the greater the production. Most specifically, aerobic exercise within the 60% to 75% of your max heart rate should be maintained for approximately 30 minutes. Don’t expect a huge boost in BDNF after just one gym session.

(Source: http://www.ncbi.nlm.nih.gov/pubmed/21282661  –  http://www.ncbi.nlm.nih.gov/pubmed/21722657)

 

2. Intermittent Fasting or Caloric Restriction

3. Dietary modifications

4. Sunlight (Vitamin D)

5. Supplements

6. Lose weight

7. Certain drugs

8. Social Enrichment

 

 

 

How exercise and aging muscles relations are?

Basically we have 4 main types of exercise:

1.Endurance

Endurance, or aerobic, activities increase your breathing and heart rate. They keep your heart, lungs, and circulatory system healthy and improve your overall fitness. Building your endurance makes it easier to carry out many of your everyday activities.

Brisk walking or jogging
Yard work (mowing, raking, digging)
Dancing
Strength

 

2. Strength exercises

Strength exercises make your muscles stronger. Even small increases in strength can make a big difference in your ability to stay independent and carry out everyday activities, such as climbing stairs and carrying groceries. These exercises also are called “strength training” or “resistance training.”

Lifting weights
Using a resistance band
Using your own body weight
Balance

 

3. Balance exercises

Balance exercises help prevent falls, a common problem in older adults. Many lower-body strength exercises also will improve your balance.

Standing on one foot
Heel-to-toe walk
Tai Chi
Flexibility

 

4. Flexibility exercises

Flexibility exercises stretch your muscles and can help your body stay limber. Being flexible gives you more freedom of movement for other exercises as well as for your everyday activities.

Shoulder and upper arm stretch
Calf stretch
Yoga

 

Almost any amount and type of physical activity may slow aging deep within our cells, a new study finds. And middle age may be a critical time to get the process rolling, at least by one common measure of cell aging. But a recent study from Cell Metabolism discovered that certain forms of exercise may increase muscle mass and mitochondrial density, particularly with people 64 and over.Not surprisingly, resistance training increased muscle mass and strength for all subjects. And cardio HIIT (high intensity interval training) improved the age-related decline in mitochondria.

For those of us who don’t know every portion of our cells’ interiors, telomeres are tiny caps found on the end of DNA strands, like plastic aglets on shoelaces. They are believed to protect the DNA from damage during cell division and replication. As a cell ages, its telomeres naturally shorten and fray. But the process can be accelerated by obesity, smoking, insomnia, diabetes and other aspects of health and lifestyle as we have talked about in all of our articles. In those cases, the affected cells age prematurely.

Exercise may slow the fraying of telomeres. Past studies have found, for instance, that master athletes typically have longer telomeres than sedentary people of the same age, as do older women who frequently walk or engage in other fairly moderate exercise.

But those studies were relatively narrow, focusing mostly on elderly people who ran or walked. It remained unclear whether people of different ages who engaged in a variety of exercises would likewise show effects on their telomeres.

So for the new study, which was published this month in Medicine & Science in Sports & Exercise, researchers from the University of Mississippi and University of California, San Francisco, decided to look more broadly at the interactions of exercise and telomeres among a wide swath of Americans.

 

 

Exercise And Ageing, Exercise Is The Key To Keep Your Body Young

Ageing is a natural part of life. Face it. As soon as you hit your twenties, you notice changes in your body that are clear signs of ageing. However, people age differently and you want to be one of those people who looks and feels younger than they actually are. You want to be as healthy and strong as you possibly can be so you can still enjoy life even in your later years.

Let’s take a look at how exercise can help you keep your body young.

As you get older, your heart muscle becomes less efficient. It works harder to pump the same amount of blood to your organs. Blood vessels also tend to lose their elasticity and hardened fatty deposits may make the supply of blood even harder. This can be avoided by eating a healthy diet with limited saturated fats, a lot of lean protein and vegetables. Consistent daily exercise will also go a long way in delaying the onset of such problems.

 

Exercise and Aging

 

One of the features of a young body is its ability to move fluidly. As you age, your bones decrease in size and density. It is even said that you lose a total of 2 inches as you grow older. Less dense bones make them prone to fracture. Muscles, joints and tendons also generally lose strength and flexibility as you get older. When you regularly exercise, your body gets used to physical activity and tries to keep up. Include weight training in your exercise regiment to keep your bones strong and your joints fluid. Proper diet will also go a long way to helping with this.

 

Exercise and Aging

 

 

Exercise the release of brain-derived neurotrophic factor (BDNF). Exercise causes a beneficial response in the brain and an increase of BDFN, which is a trophic factor which is linked to cognitive improvement and the alleviation of anxiety and depression. The levels of this protein have been found to increase after exercise. You may already have experienced this before when in an anxious state. Exercise seems to alleviate the anxiety and make you have clearer thoughts. As you get older, your mental sharpness decreases slowly. You can delay this through regular exercise from a young age.

As you get older, maintaining a healthy weight or losing weight becomes even more difficult. Given that most people tend to go into a sedentary lifestyle as they age, it may seem almost impossible. Your metabolism also slows down, meaning that you burn fewer calories. The best remedy for this is maintaining a consistent workout schedule consisting of strength and cardio workouts at least 3 times a week. This ill help you increase your ratio of lean muscle to fat. Being overweight naturally, makes you look and feel older than you actually are. You may feel like you are hurling around a heavy body everywhere you go.

Exercise and nutrition go hand in hand when considering slowing down the ageing process. One cannot do without the other.

 

 

 

Online Sources for exercise and aging:

http://onlinelibrary.wiley.com/doi/10.1113/JP271552/full

https://well.blogs.nytimes.com/2015/10/28/does-exercise-slow-the-aging-process/

mentalhealthdaily.com/2015/03/30/8-ways-to-increase-bdnf-levels-brain-derived-neurotrophic-factor/

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Papers and references for exercise and aging:

Afzalpour ME, Chadorneshin HT, Foadoddini M & Eivari HA (2015). Comparing interval and continuous exercise training regimens on neurotrophic factors in rat brain. Physiol Behav 147, 78–83.

Aimone JB, Li Y, Lee SW, Clemenson GD, Deng W & Gage FH (2014). Regulation and function of adult neurogenesis: from genes to cognition. Physiol Rev 94, 991–1026.

Allen DM, van Praag H, Ray J, Weaver Z, Winrow CJ, Carter TA, Braquet R, Harrington E, Ried T, Brown KD, Gage FH & Barlow C (2001). Ataxia telangiectasia mutated is essential during adult neurogenesis. Genes Dev 15, 554–566.

Bednarczyk MR, Aumont A, Decary S, Bergeron R & Fernandes KJ (2009). Prolonged voluntary wheel-running stimulates neural precursors in the hippocampus and forebrain of adult CD1 mice. Hippocampus 19, 913–927.

Biedermann SV, Fuss J, Steinle J, Auer MK, Dormann C, Falfán-Melgoza C, Ende G, Gass P & Weber-Fahr W (2014). The hippocampus and exercise: histological correlates of MR-detected volume changes. Brain Struct Funct doi: 10.1007/s00429-014-0976-5

Bouchard C, Blair SN, Church TS, Earnest CP, Hagberg JM, Hakkinen K, Jenkins NT, Karavirta L, Kraus WE, Leon AS, Rao DC, Sarzynski MA, Skinner JS, Slentz CA & Rankinen T (2012). Adverse metabolic response to regular exercise: is it a rare or common occurrence? PLoS One 7, e37887.

Bouchard C & Rankinen T (2001). Individual differences in response to regular physical activity. Med Sci Sports Exerc 33, S446–S451; discussion S452–S453.

Cameron HA & McKay RD (2001). Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus. J Comp Neurol 435, 406–417.

Carro E, Nuñez A, Busiguina S & Torres-Aleman I (2000). Circulating insulin-like growth factor I mediates effects of exercise on the brain. J Neurosci 20, 2926–2933.

Cassilhas RC, Lee KS, Fernandes J, Oliveira MG, Tufik S, Meeusen R & de Mello MT (2012a). Spatial memory is improved by aerobic and resistance exercise through divergent molecular mechanisms. Neuroscience 202, 309–317.

Cassilhas RC, Lee KS, Venancio DP, Oliveira MG, Tufik S & de Mello MT (2012b). Resistance exercise improves hippocampus-dependent memory. Braz J Med Biol Res 45, 1215–1220.

Castilla-Ortega E, Rosell-Valle C, Pedraza C, Rodríguez de Fonseca F, Estivill-Torrús G & Santin LJ (2014). Voluntary exercise followed by chronic stress strikingly increases mature adult-born hippocampal neurons and prevents stress-induced deficits in ‘what–when–where’ memory. Neurobiol Learn Mem 109, 62–73.

Chae CH, Jung SL, An SH, Park BY, Kim TW, Wang SW, Kim JH, Lee HC & Kim HT (2014). Swimming exercise stimulates neuro-genesis in the subventricular zone via increase in synapsin I and nerve growth factor levels. Biol Sport 31, 309–314.

Clelland CD, Choi M, Romberg C, Clemenson GD Jr, Fragniere A, Tyers P, Jessberger S, Saksida LM, Barker RA, Gage FH & Bussey TJ (2009). A functional role for adult hippocampal neurogenesis in spatial pattern separation. Science 325, 210–213.

Creer DJ, Romberg C, Saksida LM, van Praag H & Bussey TJ (2010). Running enhances spatial pattern separation in mice. Proc Natl Acad Sci USA 107, 2367–2372.

Dalla C, Papachristos EB, Whetstone AS & Shors TJ (2009). Female rats learn trace memories better than male rats and consequently retain a greater proportion of new neurons in their hippocampi. Proc Natl Acad Sci USA 106, 2927–2932.

Erickson KI, Prakash RS, Voss MW, Chaddock L, Hu L, Morris KS, White SM, Wójcicki TR, McAuley E & Kramer AF (2009). Aerobic fitness is associated with hippocampal volume in elderly humans. Hippocampus 19, 1030–1039.

Erickson KI, Voss MW, Prakash RS, Basak C, Szabo A, Chaddock L, Kim JS, Heo S, Alves H, White SM, Wojcicki TR, Mailey E, Vieira VJ, Martin SA, Pence BD, Woods JA, McAuley E & Kramer AF (2011). Exercise training increases size of hippocampus and improves memory. Proc Natl Acad Sci USA 108, 3017–3022.

Fardell JE, Vardy J, Shah JD & Johnston IN (2012). Cognitive impairments caused by oxaliplatin and 5-fluorouracil chemotherapy are ameliorated by physical activity. Psychopharmacology (Berl) 220, 183–193.

Farmer J, Zhao X, van Praag H, Wodtke K, Gage FH & Christie BR (2004). Effects of voluntary exercise on synaptic plasticity and gene expression in the dentate gyrus of adult male Sprague–Dawley rats in vivo. Neuroscience 124, 71–79.

Fischer TJ, Walker TL, Overall RW, Brandt MD & Kempermann G (2014). Acute effects of wheel running on adult hippocampal precursor cells in mice are not caused by changes in cell cycle length or S phase length. Front Neurosci 8, 314.

Gibala MJ, Little JP, Macdonald MJ & Hawley JA (2012). Physiological adaptations to low-volume, high-intensity interval training in health and disease. J Physiol 590, 1077–1084.

Gould E, Beylin A, Tanapat P, Reeves A & Shors TJ (1999). Learning enhances adult neurogenesis in the hippocampal formation. Nat Neurosci 2, 260–265.

Haram PM, Kemi OJ, Lee SJ, Bendheim MØ, Al-Share QY, Waldum HL, Gilligan LJ, Koch LG, Britton SL, Najjar SM & Wisløff U (2009). Aerobic interval training vs. continuous moderate exercise in the metabolic syndrome of rats artificially selected for low aerobic capacity. Cardiovasc Res 81, 723–732.

Hauser T, Klaus F, Lipp HP & Amrein I (2009). No effect of running and laboratory housing on adult hippocampal neurogenesis in wild caught long-tailed wood mouse. BMC Neurosci 10, 43.

Hornberger TA Jr & Farrar RP (2004). Physiological hypertrophy of the FHL muscle following 8 weeks of progressive resistance exercise in the rat. Can J Appl Physiol 29, 16–31.

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Lessard SJ, Rivas DA, Alves-Wagner AB, Hirshman MF, Gallagher IJ, Constantin-Teodosiu D, Atkins R, Greenhaff PL, Qi NR, Gustafsson T, Fielding RA, Timmons JA, Britton SL, Koch LG & Goodyear LJ (2013). Resistance to aerobic exercise training causes metabolic dysfunction and reveals novel exercise-regulated signaling networks. Diabetes 62, 2717–2727.

Leuner B, Glasper ER & Gould E (2010). Sexual experience promotes adult neurogenesis in the hippocampus despite an initial elevation in stress hormones. PLoS One 5, e11597.

Li Y, Luikart BW, Birnbaum S, Chen J, Kwon CH, Kernie SG, Bassel-Duby R & Parada LF (2008). TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment. Neuron 59, 399–412.

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Moringa Strong Antioxidant Benefits | A Polyphenol Antioxidant, Uses, Side Effects & Interactions

MORINGA, antioxidant benefits, Uses, Side Effects & Interactions

Other Names of  MORINGA: Arango, Árbol de las Perlas, Behen, Ben Ailé, Ben Nut Tree, Ben Oléifère, Benzolive, Canéficier de l’Inde, Chinto Borrego, Clarifier Tree, Drumstick Tree,…

Research in progress 

 

Moringa Strong Antioxidant Benefits | A Polyphenol Antioxidant, Uses, Side Effects & Interactions

Moringa Strong Antioxidant Benefits | A Polyphenol Antioxidant

Moringa Oleifera has been hailed since time immemorial for its immense health benefits. The plant is native to Africa and many consider it the tree of life. It is also very common in Asia as it is widely used in Ayurvedic medicine. It contains a significant number of proteins, essential vitamins, and minerals making it common not only from a nutritional point of view but also in the cosmetics industry due to its powerful antioxidants.

Moringa Strong Antioxidant Benefits | A Polyphenol Antioxidant, Uses, Side Effects & Interactions

Although Moringa has several benefits, we are going to narrow in on its antioxidant and anti-ageing properties.

Antioxidant effects of Moringa

Moringa has been found to contain about 47 antioxidants including phenolic acid, flavonoid/bioflavonoids, and tannic acid. Experiments have been carried out on different parts of the Moringa tree to identify what parts have more Polyphenol antioxidant benefits. In one study, It was found that all extracts acted as radical scavengers due to the presence of the polyphenolic compound. It was also found that the flowers possessed the highest antioxidant properties, followed closely by the leaf, root, gum bark and finally the seed.
What these strong antioxidants do is they help neutralize free radicals(oxidative damage). Free radicals are produced as by-products of normal body processes, medicine break-down after consumption and as a result of exposure to pollutants. Moringa is known as one of the most effective of antioxidant foods.

Moringa Strong Antioxidant Benefits | A Polyphenol Antioxidant, Uses, Side Effects & Interactions

Anti-aging properties of Moringa

The cosmetics industry heavily relies on Moringa as a natural supplement to try and slow down the aging process. Moringa contains a plant hormone called zeatin, which affects the process of cell division, influencing aging. Moringa is the only known plant to contain such high levels of Zeatin.

APPLIED TO THE SKIN for:
Athlete’s foot.
Dandruff.
Warts.
Skin infections.
Snakebites.
Gum disease (gingivitis).
Other conditions.
Progeria is a disease in which a person ages rapidly at a much faster rate than normal. It afflicts people whose bodies cannot manufacture and/or utilize antioxidants. Moringa contains high levels of vitamin C, which helps with the synthesis of collagen. When the level of collagen is low, the skin collapses to take up the free space, causing wrinkles, which are a tell-tale sign of aging.

Moringa Strong Antioxidant Benefits | A Polyphenol Antioxidant, Uses, Side Effects & Interactions

The anti-aging properties of Moringa do not only apply to the skin. It has been known to decrease brain aging and cognition decline. The plant is a memory booster, helping with concentration, focus, and clarity. This is by virtue of its B vitamins, but also notably, the high concentration of Iron which allows for more oxygenated blood flow to the brain.

All this information should be enough to convince you to include Moringa, in your diet. You may either take it in its natural form or as a Moringa supplement. Moringa’s antioxidant properties can also help prevent and manage certain diseases such as cancer and cardiovascular disease which stem from the overproduction of free radicals in the body. In a world where pollution is rampant, intake of antioxidant super foods is a safe bet to prevent diseases.

Moringa Strong Antioxidant Benefits | A Polyphenol Antioxidant, Uses, Side Effects & Interactions

Moringa is your best choice as it is effective, safe, naturally occurring and affordable.

 

Moringa is used to improve “tired blood” (anemia); arthritis and other joint pain (rheumatism); asthma; cancer; constipation; diabetes; diarrhea; epilepsy; stomach pain; stomach and intestinal ulcers; intestinal spasms; headache; heart problems; high blood pressure; kidney stones; fluid retention; thyroid disorders; and bacterial, fungal, viral, and parasitic infections. Moringa is also used to reduce swelling, increase sex drive (as an aphrodisiac), prevent pregnancy, boost the immune system, and increase breast milk production.

So get Moringa for :

 

 

 

 

 

Reference and resources:

sources link , Reference for more research on MORINGA:

draxe.com
webmd.com
drweil.com
examine.com
ods.od.nih.gov

http://www.webmd.com/vitamins-supplements/ingredientmono-1242-moringa.aspx?activeingredientid=1242

 

Cognitive decline and the best foods used to stop it!

Cognitive decline and the best foods used to stop it!

Antioxidant compounds, contained in fruit, vegetables and tea, have been postulated to have a protective effect against age-related cognitive decline by combating oxidative stress. However, recent research on this subject has been conflicting. here are some basic point about CD and Aging and the main focus of this Article is on foods that Helps us fight CD.

About Cognitive Decline (What is Cognitive Decline?):

If you have Cognitive Decline or cognitive impairment, you may be aware that your memory or mental function has “slipped.” Your family and close friends also may notice a change. But generally these changes aren’t severe enough to significantly interfere with your day-to-day life and usual activities.

When anyone makes some tea or use computer or even read a book, that person it utilizing the cognitive capacities. Cognitive capacities are the mental aptitudes that you have to carry from the easiest to the most perplexing task. These mental abilities incorporate mindfulness, memory, information handling and thinking. As our age increases, the cognitive abilities continuously break down. A specific sum of cognitive decrease is a typical thing in maturing. A few people may encounter an extreme crumbling in psychological abilities, prompting dementia. This can make it difficult to adapt to customary everyday tasks. In order to get rid or avoid such problems, below are some foods that can be utilized.

Mild cognitive impairment may increase your risk of later progressing to dementia, caused by Alzheimer’s disease or other neurological conditions. But some people with mild cognitive impairment never get worse, and a few eventually get better.

 

About Cognitive Decline (What is Cognitive Decline?):

 

Cognitive disorders like CD are a category of mental health disorders that primarily affect learning, memory, perception, and problem solving, and include amnesia, dementia, and delirium. While anxiety disorders, mood disorders, and psychotic disorders can also have an effect on cognitive and memory functions. Cognitive Decline is generally happening to all while aging but we dont really notice that. we get old and our abilities and awareness reduces but we dont understand maybe others do.

Cognitive decline is categorized under dementia in Mental disorders. For dementia cases, studies suggest that diets with high Omega 3 content, low in saturated fats and sugars, along with regular exercise can increase the level of brain plasticity and BDNF. Other studies have shown that mental exercise such a newly developed “computerized brain training programs” can also help build and maintain targeted specific areas of the brain.

Findings from some studies suggest that intakes of vitamin C and E that significantly exceed adequate or recommended intakes (over 130 and 15 mg/day for vitamin C and E, respectively) may be beneficial . This is in slight contrast to a very thorough review of vitamin C, cognitive decline and AD by Harrison , who concluded that a healthy, long-term diet in which adequate vitamin C levels are maintained and vitamin deficiency is avoided may protect against age-related cognitive decline and AD, and be more beneficial than taking supplements. (source & source & Source )

 

About Cognitive Decline (What is Cognitive Decline?):

 

 

Foods that are best to Slow down & stop Cognitive Decline caused by aging:

Green Tea:

Green Tea, Antioxidant effects and benefits

Green tea is on the top of the list in the skin friendly drinks due to its noteworthy storage facility of polyphenols that can cause aging. Having four glasses each day can give amazing results by fighting against aging elements in human body.

 

• GINGER ROOT:

Ginger (root) Unique health benefits & Antioxidant effects

Grated and ground ginger in two wooden spoons ginger root green leaves on the wooden board

Ginger and turmeric are from the same basic family of plants. Health benefits of turmeric is largely mentioned in many articles. But now ginger. Ginger is a Southeast Asian plant. The spice ginger is the underground rhizome of the ginger plant, known botanically as Zingiber officinale. Ginger is used as a spice and medicine.

•  TURMERIC:

Turmeric (Curcumin) Anti-inflammatory & Antioxidant Keeps you young

different types of turmeric barks

Health benefits of turmeric is largely mentioned in many articles. Turmeric is known for improving conditions for arthritis, heartburn (dyspepsia), joint pain, stomach pain, Crohn’s disease and ulcerative colitis, bypass surgery, hemorrhage, diarrhea, intestinal gas, stomach bloating, loss of appetite, stomach ulcers an so on.

•  Sage:

Sage, just a mint or strong antioxidants and Anti-Inflammatory

Sage is an herb, a mint. The leaf is used to make medicine. Sage contains rosmarinic acid, rosmarinic acid is a potent antioxidant and an anti-inflammatory agent. Rosmarinic acid reduces harmful inflammation.

Salmon:

Fish oil, DHA & EPA & OMEGA 3-6-9 Antioxidants and benefits

Raw red fish

Salmon contains astaxanthin which works amazingly on skin and enhances the elasticity of skin by decrease the number of fine lines and wrinkles.  astaxanthin is by some researches considered as the strongest antioxidant ever found.

• Fish and fish oil:

Fish oil, DHA & EPA & OMEGA 3-6-9 Antioxidants and benefits

According to the researchers after several researches, the phenomenal measure of fish they take keeps that away from dangerous heart diseases and cancer. Fish is a copious wellspring of omega-3 fats, which help avert cholesterol development in the arteries and secure against irregular heart rhythms.

•  Olive Oil & Olive extracts:

vitamin-e Unique health benefits & Antioxidant effects

Forty years back, analysts from the Seven Countries Study revealed that the monounsaturated fats found in the olive oil were to a great extent, reason of the low rates of coronary illness and cancer. Presently, the studies  indicated that olive oil additionally contains poly-phenols, effective cancer prevention agents that may help forestall age-related infections.

•  Berries:

Cranberry Strong Antioxidant Effects

All Berries, especially members of some important families, like Rosaceae (strawberry, raspberry, blackberry), and Ericaceae (blueberry, cranberry), belong to the best dietary sources of bioactive compounds (BAC). Because of the antioxidant properties of BAC, they are of great interest also for nutritionists and food technologists due to the opportunity to use BAC as functional foods ingredients. The bioactive compounds in berries contain mainly phenolic compounds (phenolic acids, flavonoids, such as anthocyanins and flavonols, and tannins) and ascorbic acid.

•  MATCHA:

Green Tea, Antioxidant effects and benefits

Matcha is basically green tea leaves that have been stone ground and processed into a powder. The powder is then filtered and raced with boiling water. Due to the difficult procedure required to deliver matcha, the tea is for the most part expensive than others.

OLIVE LEAF

branch of green olives antioxidant benefits

branch of green olives

If you are going to consider getting Olive leaf (extracts) you should know based on the studies these are the situations that it has been proven that Olive leaf (extracts) can improve.
Lowers Blood Pressure, Improves Cardiovascular Health, Diabetes, Reduces the Risk of Cancer and so on.

 

• Eggs:

Protein (amino acids) repairs all those cells that have endured the damage from free radical. Eggs, an amazing source of protein, likewise contain biotin which is an essential vitamin that protect the body from free radicals.

• Pomegranate:

The antioxidant rich fruit may help skin to make more collagen and can also help in speeding healing. The essential nutrients in it help making the skin look fresh and glower and it works amazingly as an anti aging food.

• Beans:

Beans are another protein source. They help repair cells that have endured the free radical damage. During digestion, protein separates into amino acids, the building squares of cells which further help to speed as well as repair and regenerate the skin cells along with collagen.

• Chocolate coco powder:

If dietary phenolics are active in-vivo antioxidants, chocolate can contribute a significant portion of dietary antioxidants, and the pleasant pairing of red wine and dark chocolate could have synergistic advantages beyond their complementary tastes. According to a study, the people who live in Kuna in the San Blas islands near panama, have a rate of heart illness that is a great percent less than those of Panamanians. The Kuna people, in order to stay away from heart diseases, drink a lot of a refreshments made with liberal extents of chocolate, which is bizarrely rich in flavanols that help protect the sound capacity of veins. Keeping up young veins and fights aging.

•  Watermelon:

The reviving and sweet treat contains a definitive cancer prevention agent, vitamin C, in addition to lycopene as well as potassium, which controls the adjust of water and supplements in cells and makes individuals look healthy and young.

• Dark Chocolate:

The sweet chocolate is rich in cocoa flavanols, plant compounds as well as the effective & strong antioxidant properties, which help hydrate skin and enhance circulation.

• Walnuts:

It’s the only kind of nut that contains a significant amount of unsaturated fats, which is particularly important for vegetarians who are not able to eat fish. Walnuts pack an omega-3 called alpha-linolenic corrosive. Deficiency in this fat can bring about dermatitis, which is related with dry, flaky skin. So, having walnuts will make the skin fresh, and young.

• Citrus fruits peel:

Analysts from the University of Arizona took a gander at individuals who stated that they ate citrus fruits, squeezes, and peels each week. Individuals, who ate peels such as orange peel or lemon juice, had a 33% diminished hazard for “squamous cell carcinoma”. Juices and fruit didn’t have any impact. Limonene is a compound found in the oil in the peels that offers the UV-defensive benefits and makes the skin look great.

• Walnuts:

Walnuts are stuffed with healthy as well as anti inflammatory supplements, and are the main great nut source of alpha linolenic corrosive. They help advance blood stream, which thusly takes into consideration a great delivery of oxygen to the cerebrum. What’s more, a study found that mice with the infection that were routinely nourished walnuts had enhanced memory, learning and function ability coordination.

• Coffee:

Caffeine, the gentle stimulant found in coffee actually enhances mental acuity. Beside caffeine’s mind boosting impacts, caffeine’s cell reinforcement lavishness keeps up the mental health. Also, some exploration recommends that drinking coffee can really fight with depression and anxiety in ladies and can stop cognitive decline.

• Blueberries:

Incredible things do come in little bundles, blueberries are a natural product few attempt to eat each and every. That is on the grounds that they have such a variety of extraordinary medical advantage ­while having an aftertaste like a great treat. It’s one of the most astounding cell reinforcement rich sustenance known to man, including vitamin C and vitamin K and fiber. As a result of their elevated amounts of Gallic acid, blueberries are particularly great at shielding our brains from degeneration, stress and cognitive decline.

• Broccoli:

It’s one of the best foods to improve brain health. On account of its elevated amounts of vitamin K and choline, it will help keep your memory sharp.

• Coconut oil:

It is a standout among the most flexible and bravo nourishments for brains out there. With 77 coconut oil uses and cures, there’s nothing that coconut oil can’t help. What’s more, with regards to your mental health it’s loaded with other advantages, as well. Coconut oil functions as a characteristic calming, stifling cells in charge of aggravation. It can help with memory misfortune as a person becomes older and kills terrible microbes that hang out in the guts. Hence, it’s great to stop cognitive decline in human.

• Egg Yolks:

Egg yolks contain a lot of choline, which helps in fetal mental health for pregnant ladies. It additionally separates bethane, a synthetic that produces hormones identified with bliss and fight against cognitive decline. The eggs can really make an individual happy and keep the mental health great.

• Spinach:

Spinach is rich in antioxidants, which is thought to fight against cognitive decline. What’s more, a study found that ladies who revealed eating the most verdant green and cruciferous vegetables had an especially decreased rate of cognitive decline as contrasted with the individuals who ate the minimum.

• Tomatoes:

A study found that lycopene-rich tomato helped participants prevent sunburn when they combined it with olive oil and use it for ten weeks without missing any day. Other than being an extraordinary source of strong antioxidant lycopene, tomatoes are considered a high carotenoid fruit. These nutrients may help to get rid from free radicals that can cause many diseases including aging.

 

 

 

Some good sources for cognition Decline:

http://www.mayoclinic.org/diseases-conditions/mild-cognitive-impairment/home/ovc-20206082

https://link.springer.com/article/10.1007%2Fs11130-013-0370-0

https://en.wikipedia.org/wiki/Cognitive_disorder

 

cranberry strong antioxidant effects, benefits and sideffects

Vitamin C, An antioxidant our body needs to stay healthy & prevent cancer

Olive leaf (extracts) One of the strongest antioxidants found

Olive leaf Extract One of the strongest antioxidants found, about Olive leaf Extract antioxidant benefits

Research in progress                        

Other Names of olive tree:
Acide Gras Insaturé, Acide Gras Mono-Insaturé, Acide Gras n-9, Acide Gras Oméga 9, Common Olive, Extra Virgin Olive Oil, Feuille d’Olivier, Green Olive, Huile d’Assaisonnement, Huile d’Olive

Introduction to Olive leaf extract benefits

Olive oil is has been known and used to prevent heart attack and stroke (cardiovascular disease), breast cancer, colorectal cancer, rheumatoid arthritis, and migraine headache. But Olive leaf extract comes from the leaves of olive tree, and is much different from Olive Oil. the olive leaf contains phenolics such as oleuropein, It has shown that it has protective effects against LDL oxidation also  benefits glucose metabolism for diabetes and skin health. Olive leaf is used as immune system boost for treating viral, bacterial, and other infections including influenza, swine flu, herpes, shingles, HIV/ARC/AIDS, and hepatitis B, pneumonia; chronic fatigue: tuberculosis (TB); gonorrhea; fever; malaria; dengue and infections in the teeth, ears, and urinary tract, and infections following surgery. Some Other also use it for high blood pressure, diabetes, hay fever, improving kidney and digestive function. Olive leaf kills and /or resists the multiplication of viruses, bacteria, yeasts, fungi, and other parasites in body. The olive leaf extract differ from immune boosters in that immune boosters tha stimulate your immune system to destroy disease which still requires your own energy. Olive leaf extract mainly does the work for you. it is not a supplementary for immune system it is like a parallel procedure.

vitamin-e Unique health benefits & Antioxidant effects

Proven Olive Leaf Benefits

I you are going to consider getting Olive leaf (extracts) you should know based on the studies these are the situations that it has been proven that Olive leaf (extracts) can improve.
  • Lowers Blood Pressure
  • Improves Cardiovascular Health
  • Diabetes
  • Reduces the Risk of Cancer
  • Improves Brain Function
  • Treats Arthritis
  • Kills Bacteria and Fungi
  • Improves Immune System
  • Protects Skin
  • More energy
  • Toothache relief
  • Diminished food cravings
  • Joint pain relief
  • Heartbeat regulation
  • Improved wound healing

 

branch of green olives antioxidant benefits

branch of green olives

Cancer and Olive leaf (extracts)

The Mediterranean diet which includes olive is renowned for its ability to reduce the risk of cancer as some researches say.  While numerous aspects of the diet contribute to this risk reduction, there’s growing evidence that olive oil and leaf extract contains phenolics such as oleuropein that are key components of the diet’s anti-cancer effects. Oleuropein and olive leaf extracts have numerous other mechanisms of action against cancer: They can prevent inflammation,  inflammation is another major promoter of tumor growth and olive leaf extracts are strong in fighting  inflammations.
In breast cancer cells specifically, oleuropein reduces malignant cells’ ability to respond to estrogen, the female hormone that many breast cancer cells depend on for their survival. Oleuropein stops production growth factor and the “protein-melting” enzymes that cancer cells need in order to invade healthy tissues.

Neuroprotection of Olive leaf (extracts)

Olive extracts help protect the brain neural system from the destruction brought on by age-related degenerative conditions such as Alzheimer’s and Parkinson’s diseases.  Olive extracts suppress the inflammations and reduce the damage done by oxidative stress in body cells, we did mention what oxidative stress is and how antioxidants tend to stop it from damaging our body, read more about that in our full article about Antioxidants.
Researchers found that if  the possible stroke patients be pre-treated by olive  extracts they can greatly reduce the damage after stroke. cause basically after a normal blood flow comes back after the stroke the damage gets worse. But olive extracts has shown that they change the atmosphere of the system so the come back is not that dangerous. Microscopic examination of brain tissue showed up to a 55% decrease in the volume of dying brain tissue after strokes that were pre-treated by olive extracts. Brain damages and inflammations in brain all lead to more dying neurons and cells that will lead to creating more tangles. tangles are one of the two main reasons and causes in brain aging. so Olive extracts generally work as a nice anti-age supplement.

branch of green olives antioxidant benefits

POLYPHENOLIC ANTIOXIDANTS & Olive leaf (extracts)

Polyphenolic antioxidants can help to slow down ageing by reducing cell degradation and assist in the prevention of a number of degenerative diseases. Polyphenolic antioxidants are best known in the scientific and medical communities for their ability to neutralize free radicals. The most studied polyphenolic antioxidants in Olive Leaf.
OLIVE EXTRACTS INTERACTIONS 
Moderate Interaction Be cautious with this combination
  • Medications for diabetes (Antidiabetes drugs) interacts with OLIVE
  • Medications for high blood pressure (Antihypertensive drugs) interacts with OLIVE
 

Useful Website sources and articles on Vitamin E and its benefits:


 
 
 
 
 
Phenolic compounds and antioxidant activity of olive leaf extracts.
 
 
 
 
 
 
 
 
Papers and articles for reading and references about Olive leaf (extracts):
 
 
Available at: http://www.tesisenred.net/bitstream/handle/10803/7208/tvk.pdf?sequence=1#page=30. Accessed March 8, 2013.
 
Omar SH. Oleuropein in olive and its pharmacological effects. Sci Pharm. 2010;78(2):133-54.
 
Wahle KW, Caruso D, Ochoa JJ, Quiles JL. Olive oil and modulation of cell signaling in disease prevention. Lipids.2004 Dec;39(12):1223-31.
 
Waterman E, Lockwood B. Active components and clinical applications of olive oil. Altern Med Rev. 2007 Dec;12(4):331-42.
 
Hamdi HK, Castellon R. Oleuropein, a non-toxic olive iridoid, is an anti-tumor agent and cytoskeleton disruptor. Biochem Biophys Res Commun.2005 Sep 2;334(3):769-78.
 
Ribeiro Rde A, Fiuza de Melo MM, De Barros F, Gomes C, Trolin G. Acute antihypertensive effect in conscious rats produced by some medicinal plants used in the state of Sao Paulo. J Ethnopharmacol.1986 Mar;15(3):261-9.
 
Somova LI, Shode FO, Ramnanan P, Nadar A. Antihypertensive, antiatherosclerotic and antioxidant activity of triterpenoids isolated from Olea europaea, subspecies africana leaves. J Ethnopharmacol.2003 Feb;84(2-3):299-305.
 
Khayyal MT, el-Ghazaly MA, Abdallah DM, Nassar NN, Okpanyi SN, Kreuter MH. Blood pressure lowering effect of an olive leaf extract (Olea europaea) in L-NAME induced hypertension in rats. Arzneimittelforschung.2002;52(11):797-802.
 
Cherif S, Rahal N, Haouala M, et al. A clinical trial of a titrated Olea extract in the treatment of essential arterial hypertension. J Pharm Belg. 1996 Mar-Apr;51(2):69-71.
 
Perrinjaquet-Moccetti T, Busjahn A, Schmidlin C, Schmidt A, Bradl B, Aydogan C. Food supplementation with an olive (Olea europaea L.) leaf extract reduces blood pressure in borderline hypertensive monozygotic twins. Phytother Res. 2008 Sep;22(9):1239-42.
 
Susalit E, Agus N, Effendi I, et al. Olive (Olea europaea) leaf extract effective in patients with stage-1 hypertension: comparison with Captopril. Phytomedicine.2011 Feb 15;18(4):251-8.
 
Available at: http://www.rxlist.com/capoten-drug.htm. Accessed March 11, 2013.
 
Scheffler A, Rauwald HW, Kampa B, Mann U, Mohr FW, Dhein S. Olea europaea leaf extract exerts L-type Ca(2+) channel antagonistic effects. J Ethnopharmacol.2008 Nov 20;120(2):233-40.
 
Gilani AH, Khan AU, Shah AJ, Connor J, Jabeen Q. Blood pressure lowering effect of olive is mediated through calcium channel blockade. Int J Food Sci Nutr.2005 Dec;56(8):613-20.
 
Zare L, Esmaeili-Mahani S, Abbasnejad M, et al. Oleuropein, chief constituent of olive leaf extract, prevents the development of morphine antinociceptive tolerance through inhibition of morphine-induced L-type calcium channel overexpression. Phytother Res. 2012 Nov;26(11):1731-7.
 
Visioli F, Bellosta S, Galli C. Oleuropein, the bitter principle of olives, enhances nitric oxide production by mouse macrophages. Life Sci. 1998;62(6):541-6.
 
Rocha BS, Gago B, Barbosa RM, Laranjinha J. Dietary polyphenols generate nitric oxide from nitrite in the stomach and induce smooth muscle relaxation. Toxicology.2009 Nov 9;265(1-2):41-8.
 
Palmieri D, Aliakbarian B, Casazza AA, et al. Effects of polyphenol extract from olive pomace on anoxia-induced endothelial dysfunction. Microvasc Res. 2012 May;83(3):281-9.
 
Scoditti E, Calabriso N, Massaro M, et al. Mediterranean diet polyphenols reduce inflammatory angiogenesis through MMP-9 and COX-2 inhibition in human vascular endothelial cells: A potentially protective mechanism in atherosclerotic vascular disease and cancer. Arch Biochem Biophys. 2012 Nov 15;527(2):81-9.
 
Dell’Agli M, Fagnani R, Galli GV, et al. Olive oil phenols modulate the expression of metalloproteinase 9 in THP-1 cells by acting on nuclear factor-kappaB signaling. J Agric Food Chem. 2010 Feb 24;58(4):2246-52.
 
Jemai H, Bouaziz M, Fki I, El Feki A, Sayadi S. Hypolipidimic and antioxidant activities of oleuropein and its hydrolysis derivative-rich extracts from Chemlali olive leaves. Chem Biol Interact. 2008 Nov 25;176(2-3):88-98.
 
Visioli F, Galli C. Oleuropein protects low density lipoprotein from oxidation. Life Sci. 1994;55(24):1965-71.
 
Masella R, Vari R, D’Archivio M, et al. Extra virgin olive oil biophenols inhibit cell-mediated oxidation of LDL by increasing the mRNA transcription of glutathione-related enzymes. J Nutr.2004 Apr;134(4):785-91.
 
Wang L, Geng C, Jiang L, et al. The anti-atherosclerotic effect of olive leaf extract is related to suppressed inflammatory response in rabbits with experimental atherosclerosis. Eur J Nutr. 2008 Aug;47(5):235-43.
 
Impellizzeri D, Esposito E, Mazzon E, et al. The effects of oleuropein aglycone, an olive oil compound, in a mouse model of carrageenan-induced pleurisy. Clin Nutr. 2011 Aug;30(4):533-40.
 
Carluccio MA, Siculella L, Ancora MA, et al. Olive oil and red wine antioxidant polyphenols inhibit endothelial activation: antiatherogenic properties of Mediterranean diet phytochemicals. Arterioscler Thromb Vasc Biol. 2003 Apr 1;23(4):622-9.
 
Turner R, Etienne N, Alonso MG, et al. Antioxidant and anti-atherogenic activities of olive oil phenolics. Int J Vitam Nutr Res. 2005 Jan;75(1):61-70.
 
Dell’Agli M, Fagnani R, Mitro N, et al. Minor components of olive oil modulate proatherogenic adhesion molecules involved in endothelial activation. J Agric Food Chem. 2006 May 3;54(9):3259-64.
 
Singh I, Mok M, Christensen AM, Turner AH, Hawley JA. The effects of polyphenols in olive leaves on platelet function. Nutr Metab Cardiovasc Dis. 2008 Feb;18(2):127-32.
 
Zbidi H, Salido S, Altarejos J, et al. Olive tree wood phenolic compounds with human platelet antiaggregant properties. Blood Cells Mol Dis. 2009 May-Jun;42(3):279-85.
 
Wainstein J, Ganz T, Boaz M, et al. Olive leaf extract as a hypoglycemic agent in both human diabetic subjects and in rats. J Med Food. 2012 Jul;15(7):605-10.
 
Gonzalez M, Zarzuelo A, Gamez MJ, Utrilla MP, Jimenez J, Osuna I. Hypoglycemic activity of olive leaf. Planta Med. 1992 Dec;58(6):513-5.
 
Al-Azzawie HF, Alhamdani MS. Hypoglycemic and antioxidant effect of oleuropein in alloxan-diabetic rabbits. Life Sci. 2006 Feb 16;78(12):1371-7.
 
Jemai H, El Feki A, Sayadi S. Antidiabetic and antioxidant effects of hydroxytyrosol and oleuropein from olive leaves in alloxan-diabetic rats. J Agric Food Chem. 2009 Oct 14;57(19):8798-804.
 
Eidi A, Eidi M, Darzi R. Antidiabetic effect of Olea europaea L. in normal and diabetic rats. Phytother Res. 2009 Mar;23(3):347-50.
 
Poudyal H, Campbell F, Brown L. Olive leaf extract attenuates cardiac, hepatic, and metabolic changes in high carbohydrate-, high fat-fed rats. J Nutr. 2010 May;140(5):946-53.
 
Simon D, Balkau B. Diabetes mellitus, hyperglycaemia and cancer. Diabetes Metab. 2010 Jun;36(3):182-91.
 
Kontou N, Psaltopoulou T, Soupos N, et al. Metabolic syndrome and colorectal cancer: the protective role of Mediterranean diet–a case-control study. Angiology. 2012 Jul;63(5):390-6.
 
Verberne L, Bach-Faig A, Buckland G, Serra-Majem L. Association between the Mediterranean diet and cancer risk: a review of observational studies. Nutr Cancer. 2010;62(7):860-70.
 
Anter J, Fernandez-Bedmar Z, Villatoro-Pulido M, et al. A pilot study on the DNA-protective, cytotoxic, and apoptosis-inducing properties of olive-leaf extracts. Mutat Res. 2011 Aug 16;723(2):165-70.
 
Corona G, Deiana M, Incani A, Vauzour D, Dessi MA, Spencer JP. Inhibition of p38/CREB phosphorylation and COX-2 expression by olive oil polyphenols underlies their anti-proliferative effects. Biochem Biophys Res Commun. 2007 Oct 26;362(3):606-11.
 
Kimura Y, Sumiyoshi M. Olive leaf extract and its main component oleuropein prevent chronic ultraviolet B radiation-induced skin damage and carcinogenesis in hairless mice. J Nutr. 2009 Nov;139(11):2079-86.
 
Sirianni R, Chimento A, De Luca A, et al. Oleuropein and hydroxytyrosol inhibit MCF-7 breast cancer cell proliferation interfering with ERK1/2 activation. Mol Nutr Food Res. 2010 Jun;54(6):833-40.
 
Menendez JA, Vazquez-Martin A, Oliveras-Ferraros C, et al. Analyzing effects of extra-virgin olive oil polyphenols on breast cancer-associated fatty acid synthase protein expression using reverse-phase protein microarrays. Int J Mol Med. 2008 Oct;22(4):433-9.
 
Goulas V, Exarchou V, Troganis AN, et al. Phytochemicals in olive-leaf extracts and their antiproliferative activity against cancer and endothelial cells. Mol Nutr Food Res. 2009 May;53(5):600-8.
 
Abdel-Hamid NM, El-Moselhy MA, El-Baz A. Hepatocyte lysosomal membrane stabilization by olive leaves against chemically induced hepatocellular neoplasia in rats. Int J Hepatol. 2011;2011:736581.
 
Fares R, Bazzi S, Baydoun SE, Abdel-Massih RM. The antioxidant and anti-proliferative activity of the Lebanese Olea europaea extract. Plant Foods Hum Nutr. 2011 Mar;66(1):58-63.
 
Grawish ME, Zyada MM, Zaher AR. Inhibition of 4-NQO-induced F433 rat tongue carcinogenesis by oleuropein-rich extract. Med Oncol. 2011 Dec;28(4):1163-8.
 
Acquaviva R, Di Giacomo C, Sorrenti V, et al. Antiproliferative effect of oleuropein in prostate cell lines. Int J Oncol. 2012 Jul;41(1):31-8.
 
Mohagheghi F, Bigdeli MR, Rasoulian B, Hashemi P, Pour MR. The neuroprotective effect of olive leaf extract is related to improved blood-brain barrier permeability and brain edema in rat with experimental focal cerebral ischemia. Phytomedicine. 2011 Jan 15;18(2-3):170-5.
 
Pan J, Konstas AA, Bateman B, Ortolano GA, Pile-Spellman J. Reperfusion injury following cerebral ischemia: pathophysiology, MR imaging, and potential therapies. Neuroradiology. 2007 Feb;49(2):93-102. Epub 2006 Dec 20.
 
Dekanski D, Selakovic V, Piperski V, Radulovic Z, Korenic A, Radenovic L. Protective effect of olive leaf extract on hippocampal injury induced by transient global cerebral ischemia and reperfusion in Mongolian gerbils. Phytomedicine.2011 Oct 15;18(13):1137-43.
 
Khalatbary AR, Ahmadvand H. Neuroprotective effect of oleuropein following spinal cord injury in rats. Neurol Res. 2012 Jan;34(1):44-51.
 
Bazoti FN, Bergquist J, Markides KE, Tsarbopoulos A. Noncovalent interaction between amyloid-beta-peptide (1-40) and oleuropein studied by electrospray ionization mass spectrometry. J Am Soc Mass Spectrom. 2006 Apr;17(4):568-75.
 
Daccache A, Lion C, Sibille N, et al. Oleuropein and derivatives from olives as Tau aggregation inhibitors. Neurochem Int. 2011 May;58(6):700-7.
 
Rigacci S, Guidotti V, Bucciantini M, et al. Abeta(1-42) aggregates into non-toxic amyloid assemblies in the presence of the natural polyphenol oleuropein aglycon. Curr Alzheimer Res. 2011 Dec;8(8):841-52.
 
Flemmig J, Kuchta K, Arnhold J, Rauwald HW. Olea europaea leaf (Ph.Eur.) extract as well as several of its isolated phenolics inhibit the gout-related enzyme xanthine oxidase. Phytomedicine.2011 May 15;18(7):561-6.
 
Impellizzeri D, Esposito E, Mazzon E, et al. Oleuropein aglycone, an olive oil compound, ameliorates development of arthritis caused by injection of collagen type II in mice. J Pharmacol Exp Ther.2011 Dec;339(3):859-69.
 
Gong D, Geng C, Jiang L, Wang L, Yoshimura H, Zhong L. Mechanisms of olive leaf extract-ameliorated rat arthritis caused by kaolin and carrageenan. Phytother Res. 2012 Mar;26(3):397-402.
 
Olive leaf. Monograph. Altern Med Rev. 2009 Mar;14(1):62-6.

Matcha green-tea New trending tea that burns fat and kills cancer

What are Ginkgo Biloba wonderful benefits as antioxidants and in memory and eye improvements

What are Ginkgo Biloba wonderful benefits as antioxidants and in memory and eye improvements

health benefits ginkgo tea natural-treatments-for-eye-BENEFITS & ANTIOXIDANT EFFECTS

Research in progress
GINKGO
Other Names: Abricot Argenté Japonais, Adiantifolia, Arbre aux Écus, Arbre aux Quarante Écus, Arbre du Ciel, Arbre Fossile, Bai Guo Ye, Baiguo, Extrait de Feuille de Ginkgo, Extrait de Ginkgo
 Ginkgo leaf is often taken by mouth for memory disorders including Alzheimer's disease.

Ginkgo Biloba Supplements and its Antioxidant benefits!

Ginkgo improves blood flow to the brain and acts as an antioxidant. These effects may translate into some benefits for certain medical problems, but the results have been mixed.

Some studies have found that in healthy people, ginkgo might modestly boost memory and cognitive speed. Other studies have not found a benefit. (source) Ginkgo leaf is often taken by mouth for memory disorders including Alzheimer’s disease.

About Ginkgo Biloba:

The scientific name of Ginkgo Biloba is “Salisburia adiantifolia”. It is an extract got from the leaf of the Chinese ginkgo tree which is additionally known as the maidenhair tree. The known scientific terms for extract of the green ginkgo biloba tree are EGb761 and GBE, which is regularly noted for its cerebral improving impacts. As indicated by Traditional Chinese Medicine and current clinical reviews, Ginkgo Biloba is viable, safe and it also benefits the body from various perspectives since it applies defensive impacts against mitochondrial harm and oxidative anxiety.

Amount of Ginkgo Biloba Supplements to use:

The scientific name of Ginkgo Biloba is “Salisburia adiantifolia”. It is an extract got from the leaf of the Chinese ginkgo tree which is additionally known as the maidenhair tree. The known scientific terms for extract of the green ginkgo biloba tree are EGb761 and GBE, which is regularly noted for its cerebral improving impacts. As indicated by Traditional Chinese Medicine and current clinical reviews, Ginkgo Biloba is viable, safe and it also benefits the body from various perspectives since it applies defensive impacts against mitochondrial harm and oxidative anxiety.There is no standard measurements of Ginkgo Biloba supplements to use, but, in therapeutic reviews, every clinical trial have utilized an extract of ginkgo which is standardized to 24 percent flavones glycosides along with 6 percent of terpene lactones. A typical dosage in individuals with dementia is 40ml of that concentrate three times each day. There is no standard dose of ginkgo biloba supplements. However, in medical studies, almost all clinical trials have used a standardized extract of ginkgo, standardized to 24% flavone glycosides and 6% terpene lactones. A common dose in people with dementia is 40 milligrams of that extract three times daily. For improving cognitive function in healthy people, studies have used between 120 milligrams to 600 milligrams of the extract daily.

Ginkgo Biloba:

 

Ginkgo leaf is often taken by mouth for memory disorders including Alzheimer's disease.

Ginkgo leaf is often taken by mouth for memory disorders including Alzheimer’s disease.

Effects & Benefits of Ginkgo Biloba Antioxidants:

  • Decrease depression & anxiety: In the event that you experience the ill effects of constantly high anxiety that is executing your personal satisfaction, apprehension and despondency then ginkgo may have the capacity to offer assistance. A research revealed that Ginkgo biloba antioxidants improves the body’s capacity to deal with stressors and they also neutralizes the impacts of large amounts of stress hormones such as cortisol as well as adrenaline. It raises the body’s capacity to adapt to inconvenience and stress; it may be particularly useful for individuals with generalized anxiety disorder (GAD) and conceivably regular depression, panic assaults and social fears, as well.

 

  • Enhance Memory: The antioxidants in Ginkgo biloba are very beneficial for brain due to which Ginkgo Biloba supplements are known as “Brain herb”. Studies have demonstrated that it can enhance memory in individuals with dementia. Ginkgo biloba is usually added to some soft drinks, nutrition bars along with fruit smoothies in order to lift memory and upgrade cognitive execution.

 

  • Improves the Vision and Eye health: While more confirmation is as yet required, ginkgo along with its strong antioxidants has all the earmarks of being a great supplement for eye health since it enhances blood stream to the eyes and battles free outspread harm that can hurt the cornea, macula as well as the retina. It may be particularly gainful for adults in protecting vision and bringing down UV harm or oxidative worry to eye tissue. A few reviews have observed that ginkgo biloba antioxidants are powerful at bringing down the hazard for age-related macular degeneration because of its platelet initiating variables and counteractive action of film harm created by free radicals.

  • Kills Impotency: Ginkgo biloba can also be utilized in the treatment of impotency. The primary reason of male weakness is poor dissemination and weakened blood flow through the penis, which is frequently the consequence of atherosclerosis. Since ginkgo biloba builds blood stream, it’s been found to help up to 50% of patients following six months of utilization.

 

  • Beneficial for Asthma: The antioxidants generally found in Ginko Biloba supplements helps and improve breathing. It is very beneficial for Asthma patients as it is likely to decrease the disease with the help of antioxidant reactions.

 

  • Useful for Macular Degeneration: “Macular Degeneration” is a dynamic, degenerative eye ailment that hinders the retina. It is a standout among the most widely recognized reasons for visual impairment in the US. The strong and effective antioxidants found in ginkgo biloba may help cure or mitigate some retinal issues.

 

  • Raynaud’s infection: Raynaud’s infection is actually caused by veins that over respond to the frosty and spasms, decreasing blood stream and there by denying limits of oxygen. The effective antioxidants in Ginkgo biloba may help this condition by enlarging the little veins, which would keep the spasms from totally hindering the blood stream.
Source Websites:
www.draxe.com
www.greenmedinfo.com
www.mayoclinic.org

What are Carotenoids antioxidant effects

What are Carotenoids antioxidant effects

essential_carotenoids benefits as an antioxidant

Research in progress                           

Glutathione the mother of antioxidants, but how helpful can it really be as a supplement?

What are Antioxidants & free-radicals? Antioxidants effects on aging, weight loss, Immune system

What are Antioxidants & free-radicals? Antioxidants effects on aging, weight loss, Immune system

Introduction to Antioxidant

Antioxidant
an·ti·ox·i·dant
ˌan(t)ēˈäksədənt,ˌanˌtīˈäksədənt/

“a substance that inhibits oxidation, especially one used to counteract the deterioration of stored food products. a substance that removes potentially damaging oxidizing agents in a living organism.”
What are Antioxidants & free-radicals? Antioxidants effects on aging, weight loss, Immune system
First thing that comes up in google search is what you see above. But what it really means that it removes potentially damaging oxidizing agents? what do the oxidizing agents do? what antioxidants do to them? how it helps our body with aging? how is it related to aging? Do antioxidants help your body in weight loss processes? How? Do they really keeps us young? are they same as anti-inflammatory substances? 



Lets take a closer look to the whole concept of Antioxidants.

It has been about 50 years only that even the word Antioxidant is being used. 

What are Antioxidants & free-radicals? Antioxidants effects on aging, weight loss, Immune system

The human body by its self naturally produces free radicals and the antioxidants to counteract their damaging effects, its something our body is aware of and has some solutions for it. However, in most cases, free radicals far outnumber the naturally occurring antioxidants and thats why we see that it could expedite aging and health issues. But what are free radicals? for a short answer: 

 What are Antioxidants & free-radicals? Antioxidants effects on aging, weight loss, Immune system

Free Radicals and Oxidative Damage



Human body need oxygen for its chemical activities and in order to live. the simple act of breathing is the start of the formation of highly reactive molecules called free radicals. Free radicals interact with other molecules in the body as they are in blood and metabolism, they cause Oxidative Damage. 

What are Antioxidants & free-radicals? Antioxidants effects on aging, weight loss, Immune system



Oxidative damage can result the development of a wide range of illnesses and diseases or increasing the possibility of illness by effecting the immune system. Oxidative stress occurs when the production of reactive oxygen is greater than the body’s ability to detoxify and clean the reactive intermediates. This imbalance as mentioned before leads to oxidative damage to proteins, molecules, and genes within the body. when proteins start being damaged means now all your body is in danger cause not only your muscles but all of cell’s functions even DNA functions are done by different kinds of protein. But the free radical intensity does not only depend on the body it self it depends a lot on many factor and behaviors that we  can control. Some external body causes could increase the free radicals and the damage they have on our body like:

  • Smoking (first or second hand)
  • Excessive exposure to UV rays
  • Pollution
  • Eating an unhealthy diet
  • Certain medications and/or treatments
  • Excessive exercise
  • Breathing deep and enough



What are Antioxidants & free-radicals? Antioxidants effects on aging, weight loss, Immune system


How Free Radicals are Formed



Normally, in our body bonds dont lag, they dont split in a way that leaves a molecule with an odd (unstable condition or harmful situation), unpaired electron. But when weak bonds split, free radicals are formed. Free radicals are very unstable it means they can react and bond quickly with many potentialities and affect quickly the other compounds, trying to capture the needed electron to gain stability. 

Some internally generated sources of free radicals are:

  • Mitochondria
  • Xanthine oxidase
  • Peroxisomes
  • Inflammation
  • Phagocytosis
  • Arachidonate pathways
  • Exercise
  • Ischemia/reperfusion injury
  • Some externally generated sources of free radicals are:
  • Cigarette smoke
  • Environmental pollutants
  • Radiation
  • Certain drugs, pesticides
  • Industrial solvents
  • Ozone


Generally, free radicals attack (try to bond and become stable) the nearest stable molecule, “stealing” its electron. When the “attacked” molecule loses its electron, it becomes a free radical itself and causing this in a mass scale in body by beginning a chain reaction. Once the process is started, it can cascade, finally resulting in the disruption of a living cell. Cells are smallest stable and almost independent units in our body. every and each one of them are playing an important role in what an organ and bigger part does. It means they are independent but they also work as a team and they communicate, so if something goes wrong in one specially in RNA/DNA level it will spread. they communicate with substances and some other factors so many effects that free radicals have can be very local and at the same time in whole body.


What are Antioxidants & free-radicals? Antioxidants effects on aging, weight loss, Immune system

Our body sometimes uses the free radicals. basically our body pretty much knows what they are and some free radicals arise normally during metabolism. Sometimes the body immune systems cells or white blood cells purposefully create them to neutralize viruses and bacteria, well that is as smart as it can get. However, environmental factors such as pollution, radiation, cigarette smoke and herbicides can also increase free radicals unnaturally. Usually The body handles free radicals, but if antioxidants are unavailable, or if the free-radical production becomes excessive, damage can occur. 


Of particular importance is that free radical damage accumulates with age. Yes aging can be expedited by free radicals. they make your body an unsafe place to live for cells. they interfere with metabolism and damage the immune system and their number one scary result can be cancer. 


Antioxidants Counteract Oxidative Stress and Free Radicals
The body is aware of its substances it naturally produces antioxidants like superoxide dismutase, catalase, or peroxidase enzymes, as a means of defending itself against free radicals. The antioxidants neutralize the free radicals, so makes them harmless to other cells. Antioxidants can repair damaged molecules in body by donating hydrogen atoms to them. Some antioxidants even have a chelating effect on free radical production that’s catalyzed by heavy metals. In this situation, the antioxidant contains the heavy metal molecules so strongly that the chemical reaction necessary to create a
free radical never occurs. When these kinds of antioxidants are water-soluble, it also causes the removal of the heavy metals from the body via the urine. for example Astaxanthin is in some cases considered nature’s most powerful antioxidant in foods and also available in pills and supplements now.



What are Antioxidants & free-radicals? Antioxidants effects on aging, weight loss, Immune system

Different Types of Antioxidants

 

All the antioxidants are different and function different. Astaxanthin is actually a lipid-soluble antioxidant, while resveratrol is a water-soluble antioxidant And Each type of them function in its own way. antioxidants can be categorized in tow different ways, as a matter of fact three but molecular size is not an effective issue in terms of choosing what to take for you.


1. Antioxidants can be categorized basically in two categories:

 

Soluble in lipids/fat (hydrophobic) or water (hydrophilic). Both of them are neede in body in order to protect your cells. basically because body cells have both environments in them and as a matter of facts the interior of your cells and the fluid between them are composed of water, while the cell membranes themselves are mostly made of fat. The free radicals can strike both the watery cell contents or the fatty cellular membrane. Lipid-soluble antioxidants are the ones that protect your cell membranes from lipid peroxidation. Some examples of lipid-soluble antioxidants are vitamins A and E, carotenoids, and lipoic acid. Water-soluble antioxidants are found in aqueous fluids, like your blood and the fluids examples of water-soluble antioxidants are vitamin C, polyphenols, and glutathione.


2. They can also be categorized in another way as enzymatic and non-enzymatic antioxidants:


Enzymatic antioxidants benefit you by breaking down the structure of the free radicals and removing free radicals from your system. They can flush out dangerous oxidative products by converting them into hydrogen peroxide, then into water and gone you are free of free radicals.

Non-enzymatic antioxidants benefit you by interrupting free radical chain reactions that is another way to block them from damaging the whole environment. Some examples are carotenoids, vitamin C, vitamin E, plant polyphenols, and glutathione (GSH). Most antioxidants found in supplements and foods are non-enzymatic.



What are Antioxidants & free-radicals? Antioxidants effects on aging, weight loss, Immune system

 
What are Antioxidants & free-radicals? Antioxidants effects on aging, weight loss, Immune systemAstaxanthin has an especially high propensity for absorbing the excess energy from singlet oxygen, releasing it as heat, and returning the oxygen (and itself) back to its original state. This process is known as “quenching.”  Because of very different structures of all the molecules we call antioxidants the actual chemical procedure is different and the effectiveness and the way they can help the body is different. 

Why may Antioxidant Supplements do not work as well as foods Work?

Some Clinical and scientific studies of antioxidant supplements have not found them to be as effective as expected. Researchers have suggested several reasons:
 
> The Antioxidant beneficial health effects of a diet high in vegetables and fruits or other antioxidant-rich foods may actually be caused by other substances. that we dont know about them.
 
> Problem with doses. The effects of the large doses of antioxidants used in supplementation studies may be different from the smaller doses in natural foods.
 
> Differences in the chemical composition of antioxidants, For example, eight chemical forms of vitamin E are present in natural foods. but only two in Vitamin E supplements like alpha-tocopherol. Alpha-tocopherol also has been used in almost all research studies on vitamin E.


ALPHA - LIPOIC ACID What are Antioxidants & free-radicals? Antioxidants effects on aging, weight loss, Immune system

Good natural sources for Vitemin C, vitamin A and vitamin E as the most popular antioxidants:


Good Food Sources of Vitamin C (mg/serving)

Food
Amount
Vitamin C
Orange juice, fresh squeezed
1 cup
124
Grapefruit juice, fresh squeezed
1 cup
94
Papaya
1/2 medium
94
Cantaloupe
1/4 melon
86
Orange
1 medium
80
Green peppers, raw chopped
1/2 cup
67
Tomato juice
1 cup
44
Strawberries
1/2 cup
43
Broccoli, raw chopped
1/2 cup
41
Grapefruit
1/2 medium
40
Source: USDA Nutrient Database for Standard Reference Release 13
 

Good Food Sources of Vitamin E (mg/serving)

Food
Amount
Vitamin E
Almonds
1/4 cup
9.3 (13.9 IU)
Sunflower seeds
1/4 cup
5.8 (8.7 IU)
Safflower oil
1 tbsp
4.7 (7.0 IU)
Peanuts
1/4 cup
3.3 (4.9 IU)
Peanut butter
2 tbsp
3.2 (4.8 IU)
Corn oil
1 tbsp
2.8 (4.2 IU)

Good Food Sources of Vitamin A  


Food                                                      mcg RAE perserving    IU per serving   Percent DV*


Sweet potato, baked in skin, 1 whole        1,403               28,058         561

Beef liver, pan fried, 3 ounces                   6,5822             2,175          444
Spinach, frozen, boiled, ½ cup                  5731                1,458          229
Carrots, raw, ½ cup                                 459                  9,189          184
Pumpkin pie,  1 piece                              488                   3,743          249
Cantaloupe, raw, ½ cup                           135                   2,706          54
Peppers, sweet, red, raw, ½ cup               117                   2,332          47
Mangos, raw, 1 whole                              112                   2,240          45
Black-eyed peas (cowpeas),boiled, 1 cup   66                     1,305          26
Apricots, dried, sulfured, 10 halves            63                    1,261          25
Broccoli, boiled, ½ cup                              60                    1,208          24
Ice cream, French vanilla, soft serve, 1 cup 278                 1,014           20
Cheese, ricotta, part skim, 1 cup                263                  945             19
Tomato juice, canned, ¾ cup                     42                    821             16
Herring, Atlantic, pickled, 3 ounces            219                   731            15



Some important questions about antioxidants:

 


Where are antioxidants? 

 
They are naturally in foods and vegetables and fruits. some of them have more some less but still they are the best source comparing to supplements. Means eating fish regularly is better that fish oil supplements only. 
 

How can we get them? 

 
IN foods and vegetables and fruits. Also available in supplements. but in some cases it is better to take the natural option than just the pill.
 

Do natural sources work the same as supplements in terms of antioxidants? 

 
In some cases ye sand some no. 
 

What is the strongest antioxidant?

 
I n some cases they say its DHA fish oil and in some cases Astaxanthin in terms of effects in what part of cell or body. And in some cases olive extracts also has been mentioned. For example DHA in fish oils improve the brain plasticity/ BDNF and is the best in therms of brain aging. but it is different in all the body.
 

Is there a list of antioxidants?

 
Yes you can find a complete list of antioxidants in our website: antioxidants list
 

Antioxidants are effective more in natural forms like food or pills/ tablets/ supplements? 

 
The researches has shown that it depends on the issue and on the antioxidant substance. in some cases because of the different doses and absorbent quality the food id much better and in some cases it can be the same. 
 

What foods are high in antioxidants?

 
Fish, fish oils, vegetables, fruits and so on are the natural sources. there are also extracts in supplements that can do the job in some cases. 
 

What do antioxidants do? or what are the benefits of antioxidants ?

 
Just read the article please
 

Do antioxidants cure cancer? 

 
No, not exactly. but they can improve the symptoms and reduce the possibility of getting cancer.
 

Do antioxidants prevent cancer?

 
In many researches the free radicals are the ones causing cancer or increasing the chance to get cancer but if you get enough antioxidants for sure you are reducing the chance of cancer. it does apply to many cancer types but to all.
 

Are antioxidants the same as vitamins? 

 
Yes an some cases like vitamin E or C or A. but not all of them are considered as vitamins. 
 

 

Which diseases can be healed and/or cured by antioxidants?

It is not limited to these diseases or body conditions but these are the most associated ones with antioxidants

 

This can be a very small and useful list of them but in fact as mentioned antioxidants are substances fighting Degenerative Diseases effecting both immune system and DNA in many levels this list of Degenerative Diseases can also be considered.

Categorization of Degenerative Diseases

  • Neoplasms (divisions of mutated cells)

               – Examples:

                Cancer

                Tumor

  • Diseases of the Blood
  • Endocrine Diseases

                – Examples:

                 Thyroidism

  • Metabolic Syndrome (is a cluster of conditions – high blood pressure, high blood sugar, excess body fat (typically around the waist) and high level of bad cholesterol or low level of good cholesterol)

               – Examples:

                  Diabetes 

                  Hyperlipidemia (high level of fats in the blood)

                  Arteriosclerosis (thickening and hardening of artery walls)

                  Fatty Liver (build up of fats in the liver)

                  Hypertension (high blood pressure)

                  Obesity (being over weight)

  • Diseases of the Nervous System
  • Diseases of the Eye and Adnexa
  • Diseases of the Ear and Mastoid Process
  • Diseases of the Circulatory System
  • Diseases of the Respiratory System
  • Diseases of the Skin and Subcutaneous Tissue
  • Diseases of the Musculoskeletal System and Connective Tissue
  • Diseases of the Genitourinary System
  • Ischemia (restriction or cut-off of blood supply)/reperfusion (restoration of blood supply) injuries

                – Examples:

                   Cerebral Infraction (stroke caused by blockage)

                   Myocardial infraction (heart attack)

                   Organ transplant 

                   Post Cardiac Arrest (resuscitated heart after the heart stopped)

  • Mitochondrial Diseases
  • Aging

                – Examples:

                   Wrinkles,

                   Freckles

  • Hemodialysis

                – Examples:

                   Cystisis

  • Inflammation

                – Examples:

                  Rhematoid arthritis

                  Wound healing

                  Bowel disease

  • Neuroprotection

                – Examples:

                   Dementia

                   Parkinson Disease

                   Depression

  • Medication Induced

               – Examples:

                  Anesthetia

                  Radiatheraphy

                 Chemotheraphy

  • Stress Induced

               – Examples:

                 Exercise

                 Fatigue

Antioxidants Also Combat Infectious Diseases in basically two main ways:


1- Building or maintaining very healthy immune cells to fight the invasion
2- Countering the cell damages caused by the invasions/infections

 
And this is a good list of diseases caused by infections that can be improved by antioxidants and the most popular one whit fighting infections is vitamin C.


  • Bacteria Infections
               – Examples:
                 Strep throat
                 Tuberculosis
                 Urinary tract infections (UTI)
  • Virus Infections
               – Examples:   
                  AIDS
                 Common cold
                 Ebola hemorrhagic fever
                 Genital herpes
                 Influenza
                Measles
                Chickenpox and shingles
  • Fungi Infections
              – Examples:
                 Thrush
                 Athlete’s foot
                 Ringworm
  • Protozoa Infections
                – Examples:
                  Giardia
                  Malaria
                  Toxoplasmosis
  • Helminths Infections
                – Examples:
                   Tapeworm infection
                   Roundworms infection
                   Heartworms infection

Do antioxidants help in weight loss? or Do antioxidants help us lose weight?

 
Yes and NO. Well Not exactly, the antioxidants effectdoes not directly effect your body fat. But help a lot in body metabolism that can be said that it indirectly helps with losing weights by iproving body metabolism and blod stream.
but it is very important to know that many fruits and also extracts that are considered for their antioxidants effects has shown in researches that they also have benefits in loosing weight like Vitamin E or Green Tea and so on.











Sources in web and scientific articles on antioxidants, free radicals and oxidation:


nutrex-hawaii.com

news-medical.net
ncbi.nlm.nih.gov
cancer.gov
google.com
simplyantioxidant.com

……………………………………………………………………………………………………………………………………………………………………………………………………………………………….

 

Some handy articles on antioxidants, free radicals and oxidation:
 
 

 

list of articles:

1. Halliwell B, Gutteridge JMC. Free radicals in biology and medicine. 4th. Oxford, UK: Clarendon Press; 2007.

2. Bahorun T, Soobrattee MA, Luximon-Ramma V, Aruoma OI. Free radicals and antioxidants in cardiovascular health and disease. Internet J. Med. Update. 2006;1:1–17.

3. Valko M, Izakovic M, Mazur M, Rhodes CJ, et al. Role of oxygen radicals in DNA damage and cancer incidence. Mol. Cell Biochem. 2004;266:37–56. [PubMed]

4. Valko M, Leibfritz D, Moncola J, Cronin MD, et al. Free radicals and antioxidants in normal physiological functions and human disease. Review. Int. J. Biochem. Cell Biol. 2007;39:44–84. [PubMed]

5. Droge W. Free radicals in the physiological control of cell function. Review. Physiol. Rev. 2002;82:47–95.[PubMed]

6. Willcox JK, Ash SL, Catignani GL. Antioxidants and prevention of chronic disease. Review. Crit. Rev. Food. Sci. Nutr. 2004;44:275–295. [PubMed]

7. Pacher P, Beckman JS, Liaudet L. Nitric oxide and peroxynitrite in health and disease. Physiol. Rev. 2007;87:315–424. [PMC free article] [PubMed]

8. Genestra M. Oxyl radicals, redox-sensitive signalling cascades and antioxidants. Review. Cell Signal. 2007;19:1807–1819. [PubMed]

9. Halliwell B. Biochemistry of oxidative stress. Biochem. Soc. Trans. 2007;35:1147–1150. [PubMed]

10. Young I, Woodside J. Antioxidants in health and disease. J. Clin. Pathol. 2001;54:176–186.[PMC free article] [PubMed]

11. Valko M, Rhodes CJ, Moncol J, Izakovic M, et al. Free radicals, metals and antioxidants in oxidative stress-induced cancer. Mini-review. Chem. Biol. Interact. 2006;160:1–40. [PubMed]

12. Valko M, Morris H, Cronin MTD. Metals, toxicity and oxidative stress. Curr. Med. Chem. 2005;12:1161–1208. [PubMed]

13. Parthasarathy S, Santanam N, Ramachandran S, Meilhac O. Oxidants and antioxidants in atherogenesis: an appraisal. J. Lipid Res. 1999;40:2143–2157. [PubMed]

14. Frei B. Reactive oxygen species and antioxidant vitamins. Linus Pauling Institute. Oregon State University. 1997 http://lpi.oregonstate.edu/f-w97/reactive.html .

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17. Halliwell B. Role of free radicals in neurodegenerative diseases: therapeutic implications for antioxidant treatment. Drugs Aging. 2001;18:685–716. [PubMed]

18. Singh RP, Sharad S, Kapur S. Free radicals and oxidative stress in neurodegenerative diseases: Relevance of Dietary Antioxidants. JIACM. 2004;5:218–225.

19. Christen Y. Oxidative stress and Alzheimer disease. Am. J. Clin. Nutr. 2000;71:621S–629S. [PubMed]

20. Butterfield DA. Amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity: implications for neurodegeneration in Alzheimer’s disease brain. A review. Free Radic. Res. 2002;36:1307–1313. [PubMed]

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22. Guo RF, Ward PA. Role of oxidants in lung injury during sepsis. Antioxid. Redox. Signal. 2007;9:1991–2002. [PubMed]

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30. Massicot F, Lamouri A, Martin C, Pham-Huy C, et al. Preventive effects of two PAF-antagonists, PMS 536 and PMS 549, on cyclosporin-induced LLC-PK1 oxidative injury. J. Lipid Mediat. Cell Signal. 1997;15:203–214. [PubMed]

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